【New Publication】Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesis

Li lab published a preprint in bioRxiv entitled “Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesis.” In this research article, an expandable, 3D branching ureteric bud (UB) organoid culture model has been generated. The UB organoid can be derived from primary UB progenitors from mouse and human fetal kidneys, or Read More…

【New Publication】Epigenetic Regulation of Kidney Progenitor Cells

Li lab published an article entitled “Epigenetic Regulation of Kidney Progenitor Cells” in STEM CELLS Translational Medicine. In this review article, current understanding of epigenetic mechanisms involved in the cell fate determination of various kidney progenitor cells, including nephron progenitor cells, ureteric bud progenitor cells, and interstitial progenitor cells, have been summarized. And the potential contribution Read More…

【New Publication】Gene Editing in 3D Cultured Nephron Progenitor Cell Lines

Dr. Zhongwei Li, together with Dr. Toshikazu Araoka from Center for iPS Cell Research and Application (CiRA) in Japan, and Dr. Juan Carlos Izpisua Belmonte from Salk Institute, published a book chapter in a new Springer book “Kidney Organogenesis: Methods and Protocols”. In this new book chapter entitled “Gene Editing in 3D Cultured Nephron Progenitor Read More…