2023
1. Impact of Bacteria Types on the Clinical Outcomes of Spontaneous Bacterial Peritonitis. Digestive Diseases and Sciences (2023). 68(5):2140-2148. doi: 10.1007/s10620-023-07867-8. PMID: 36879176. Furey C, Zhou S, Park JH, Foong A, Chowdhury A, Dawit A, Lee V, Vergara-Lluri M, She R, Kahn JA, Dodge JL, Saito T.
2. Long-Term Cell Fate and Functional Maintenance of Human Hepatocyte through Stepwise Culture Configuration. FASEB Journal (2023). 37(2):e22750. doi: 10.1096/fj.202201292RR. PMID: 36607308. Sugahara G, Ishida Y, Lee JJ, Li M, Tanaka Y, Eoh H, Higuchi Y, Saito T
3. Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response. JCI Insight (2023). 8(9):e162404. doi: 10.1172/jci.insight.162404. PMID: 37154158. Chida T, Ishida Y, Morioka S, Sugahara G, Han C, Lam B, Yamasaki C, Sugahara R, Li M, Tanaka Y, Liang TJ, Tateno C, and Saito T.
4. Guiding Hepatic Differentiation of Pluripotent Stem Cells Using 3D Microfluidic Co-Cultures with Human Hepatocytes. Fattahi P, De Hoyos-Vega JM, Choi JH, Duffy CD, Gonzalez-Suarez AM, Ishida Y, Nguyen KM, Gwon K, Peterson QP, Saito T, Stybayeva G, Revzin A. Cells (2023).
5. Clinical Significance of Ascitic Fluid Polymorphonuclear Leukocyte (PMN) Percentage in Cirrhosis Patients without Spontaneous Bacterial Peritonitis (SBP). Dawit L, Lee V, Lehoang D, Furey C, Chowdhury A, Mai TA, Angajala V, Park JH, Khadarian K, She R, Vergara-Lluri M, Kahn J, Dodge, JL, Saito T. Clinical and Translational Gastroenterology (2023).
6. Function of hepatocyte spheroids in bioactive microcapsules is enhanced by endogenous and exogenous hepatocyte growth factor. Gwon K, Choi D, de Hoyos-Vega JM, Baskaran H, Gonzalez-Suarez AM, Lee S, Hong HJ, Nguyen KM, Dharmesh E, Sugahara G, Ishida Y, Saito T, Stybayeva G, Revzin A. Bioactive Materials (2023).
7. Hepatocellular organellar abnormalities following elimination of hepatitis C virus. Aoyagi H, Iijima H, Gaber E. S, Zaitsu T, Matsuda M, Wakae K, Watashi K, Suzuki R, Masaki T, Kahn J, Saito T, El-Kassas M, Shimada N, Kato K, Enomoto M, Hayashi K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Muramatsu M, Wake K, Wakita T, Aizaki H. Liver International (2023).
2022
1. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1beta to downregulate PPARalpha and FOXO3. Cell Report (2022): 38(4):110284. PMID: 35081341. Li Y, Zhu Y, Feng S, Ishida Y, Chiu TP, Saito T, Wang S, Ann DK, Ou JJ.
2. Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis. Transplant International (2022). PMID: 35368647. Horwich BH, Liang TZ, Dodge JL, Chopra S, Kahn JA, Saito T.
3. Reply to: Comments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis. Transplant International (2022). PMC9389643. Horwich BH, Kahn JA, Saito T.
4. Development and characterization of secondary standards for nucleic acid amplification technology (NAAT) assays for detection of hepatitis E virus. J Clin Virol (2022). PMID: 36395548. Fares-Gusmao, R, Jiang Z, Subramaniam S, Visser BJ, Scott A, Ishida Y, Saito T, Baylis SA, McGivern DR, H. E. V. Standard Calibration Study Group.
5. Downregulation of SOCS1 increases interferon-induced ISGylation during differentiation of induced-pluripotent stem cells to hepatocytes. JHEP Rep (2022) PMID: 36439639. Edwards JS, Delabat SA, Badilla AD, DiCaprio RC, Hyun J, Burgess RA, Silva T, Dykxhoorn DM, Chen SX, Wang L, Ishida Y, Saito T, Thomas E.
6. Loss of mitochondrial ATPase ATAD3A contributes to non-alcoholic fatty liver disease through accumulation of lipids and damaged mitochondria. J Biol Chem. (2022) PMID: 35513069 . Chen L, Li Y, Sottas C, Lazaris A, Petrillo SK, Metrakos P, Li L, Ishida Y, Saito T, Garza S, Papadopoulos V.
7. Autophagic membranes participate in hepatitis B virus nucleocapsid assembly, precore and core protein trafficking, and viral release. Proc Natl Acad Sci U S A (2022). PMID: 35858426. Chu JYK, Chuang YC, Tsai KN, Pantuso J, Ishida Y, Saito T, Ou, J. J.
2021
1. Lipoprotein Z, a novel hepatotoxic lipoprotein, predicts outcome in alcoholic hepatitis. Hepatology 2021. PMID: 34662439. Hu K, Perez-Matos MC, Argemi J, Vilar, Shalaurova I, Bullitt E, Landeen L, Sugahara G, Deng H, Mathur K, Tran S, Cai H, He H, Yalcin Y, Barbosa JV, Ventura-Cots M, Marx K, Gad AP, Niezen S, Barba SI, Ang LH, Popov YV, Fricker Z, Lai M, Curry M, Afdhal N, Szabo G, Mukamal KJ, Sanyal AJ, Otvos JD, Malik R, Saito T, Connelly MA, Chalasani NP, Bataller R, Jiang ZG.
2. Infection courses, virological features and IFN-alpha responses of HBV genotypes in cell culture and animal models. Journal of Hepatology 2021. PMID: 34363922. Zhang M, Zhang Z, Imamura M, Osawa M, Teraoka Y, Piotrowski J, Ishida Y, Sozzi V, Revil PA, Saito T, Chayama K, Liang TJ.
3. Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease. iScience 2021; 24(1):102457. PMID: 34013171. Li Y, Chen L, Li L, Sottas C, Petrillo S, Lazaris A, Metrakos P, Wu H, Ishida Y, Saito T, Golden-Mason L, Rosen HR, Wolff JJ, Silvescu CI, Garza S, Cheung G, Huang T, Fan J, Culty M, Stiles B, Asahina K, Papadopoulos V.
4. Suppression of hepatitis B virus through therapeutic activation of RIG-I and IRF3 signaling in hepatocytes. iScience 2021; 24(1). Lee S, Goyal A, Perelson AS, Ishida Y, Saito T, Gale M Jr.
5. A Case of Benign Hepatic Cyst with Supra-elevated Cyst Fluid Tumor Markers. Dig Dis Sci. 2021. PMID: 33403484 DOI: 10.1007/s10620-020-06727-z. Tonthat A, Bui D, Romero M, Lo E, Kanel G, Saito T.
2020
1. Art of Making Artificial Liver: Depicting Human Liver Biology and Diseases in Mice. Sugahara G, Ishida Y, Sun J, Tateno C, Saito T. Seminars in Liver Diseases. 2020 Feb 19. doi: 10.1055/s-0040-1701444. PMID: 32074631
2. High Prevalence of Chronic Viral Hepatitis and Liver Fibrosis Among Mongols in Southern California. Fong TL, Lee BT, Chang M, Nasanbayar K, Tsogtoo E, Boldbaatar D, Dashdorj ED, Clifford NE, Dashdorj AN, Bang BR, Chida T, Lim C, Sugiyama M, Mizokami M, Dashdorj NJ, Liu P, Glenn JS, Dashdorj ND, Saito T. Dig Dis Sci. 2020. doi: 10.1007/s10620-020-06499-6. PMID: 32770488
2019
1. Hepatic IFN-induced protein with tetratricopeptide repeats Regulation of HCV Infection. Ishida Y, Kakuni M, Bang BR, Sugahara G, Lau DT, Tateno-Mukaidani C, Li M, Gale M Jr, and Saito T. Journal of Interferon & Cytokine Research.
2. Regulation of HCV infection by Cellular Retinoic Acid Binding Proteins through the modulation of lipid droplet abundance. Bang BR, Li M, Tsai KN, Aoyagi H, Lee SA, Machida K, Aizaki H, Jung JU, Ou JJ, Saito T. Journal of Virology. 2019; PMID: 30728260
3. Balog S, Li Y, Ogawa T, Miki T, Saito T, French SW, Asahina K. Development of Capsular Fibrosis beneath the Liver Surface in Humans and Mice. Hepatology. 2019; PMID: 31206736
4. IFN-Independent ISG Expression and its Role in Antiviral Cell-Intrinsic Innate Immunity. Thomas E, Saito T. Viruses. 2019; PMID 31653097. Oct 24;11(11). pii: E981. doi: 10.3390/v11110981.
2017
1. Reply. Kahn J and Saito T. Gastroenterology 2017; 153: 328-329
2. Dual Modulation of Human Hepatic Zonation via Canonical and Non-Canonical Wnt Pathways. McEnerney K, Duncan K, Bang BR, Elmasry S, Li M, Miki T, Ramakrishnan SK, Shah YM, Saito T. Experimental & Molecular Medicine (2017) 49, e413 doi:10.1038/emm.2017.226
2016
1. Organ system view of the hepatic innate immunity in HCV infection. Bang BR, Elmasry S, Saito T. J Med Virol. 2016 May 6. doi: 10.1002/jmv.24569.
2. Detection of Occult Hepatitis C Virus Infection in Patients Who Achieved a Sustained Virologic Response to Direct-acting Antiviral Agents for Recurrent Infection After Liver Transplantation. Elmasry S, Wadhwa S1, Bang BR, Cook L, Chopra S, Kanel G, Kim B, Harper T, Feng Z, Jerome KR, Kahn J, Saito T. Gastroenterology. 2016; PMID: 27838287
3. Comparison of Demographic and Clinical Characteristics of Hispanic and Asian Chronic Hepatitis B Patients in Southern California. Zhu J, Khemichian S, Nghiem D, Zhang SR, Limurti J, Saito T, Fong TL. Journal of Clinical Gastroenterology. 2016; 50 (7):602-7
2015
1. An internally translated variant of MAVS exposes its amino-terminal TRAF-binding motifs to deregulate interferon induction. Minassian A, Zhang J, He S, Zhao J, Zandi E, Saito T, Liang C, Feng P. PLOS Pathogen 2015: 11(7) e1005060
2. Retinoid Regulation of Antiviral Innate Immunity in Hepatocytes. Cho NE, Bang BR, Gurung P, Li M, Clemens DL, Underhill TM, James LP, Chase JR Saito T. Hepatology 2015
2014
1. Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1. Ooi EL, Chan ST, Cho NE, Wilkins C, Woodward J, Li M, Kikkawa U, Tellinghuisen T, Gale M Jr, Saito T. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1909-14.
2013
1. Innate Immune Tolerance and the Role of Kupffer Cells in Differential Responses to Interferon Therapy Among Patients with HCV Genotype 1 Infection. Lau DT, Negash A, Chen J, Crochet N, Sinha M, Zhang Y, Guedj J, Holder S, Saito T, Lemon SM, Luxon BA, Perelson AS, Gale M Jr. GASTROENTEROLOGY 2013;144:402– 413