Publications

PUBLICATIONS

1. Gender-Specific Risk Factors for Reflux Esophagitis in a Predominantly Hispanic Population of a Large Safety-Net Hospital. Haghighat S, Park C, Horwich B, Liu Y, Soffer E, Idos G, Shaker A. Dig Dis Sci. 2020 Jul 20. doi: 10.1007/s10620-020-06482-1. [Epub ahead of print] PMID: 32691385
2. Human esophageal myofibroblasts increase squamous epithelial thickness via paracrine mechanisms in an in vitro model of gastroesophageal reflux disease. Hu L, Zhang C, Yang K, Li M, Shaker A.PLoS One. 2020 Sep 14;15(9):e0238852. doi: 10.1371/journal.pone.0238852. eCollection 2020.
3. Human esophageal myofibroblast secretion of bone morphogenetic proteins and GREMLIN1 and paracrine regulation of squamous epithelial growth.Zhang C, Niu C, Yang K, Shaker A. Sci Rep. 2018 Aug 17;8(1):12354. doi: 10.1038/s41598-018-30799-7. PMID: 30120338
4. Pharmacological and other treatment modalities for esophageal pain. Hoff DA, Brock C, Farmer AD, Dickman R, Ruffle JK, Shaker A, Drewes AM. Ann N Y Acad Sci. 2016 Sep;1380(1):58-66. doi: 10.1111/nyas.13151. Epub 2016 Jul 21. Review. PMID: 27442914
5. Contribution of immunomodulators to gastroesophageal reflux disease and its complications: stromal cells, interleukin 4, and adiponectin.Li J, Chen XL, Shaker A, Oshima T, Shan J, Miwa H, Feng C, Zhang J.Ann N Y Acad Sci. 2016 Sep;1380(1):183-194. doi: 10.1111/nyas.13157. Epub 2016 Jul 21. Review. PMID: 27441783
6. Provocative testing of the esophagus and its future.Farmer AD, Franchina M, Gregersen H, Penagini R, Shaker A, Soffer E. Ann N Y Acad Sci. 2016 Sep;1380(1):33-47. doi: 10.1111/nyas.13109. Epub 2016 Jun 16. Review.PMID:27311061
7. Generation and Characterization of an Immortalized Human Esophageal Myofibroblast Line. Niu C, Chauhan U, Gargus M, Shaker A. PLoS One. 2016 Apr 7;11(4):e0153185. doi: 10.1371/journal.pone.0153185. eCollection 2016. PMID: 27055018
8. Human esophageal myofibroblasts secrete proinflammatory cytokines in response to acid and Toll-like receptor 4 ligands. Gargus M, Niu C, Vallone JG, Binkley J, Rubin DC, Shaker A. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 1;308(11):G904-23. PMID: 25882613
9. Isolation of myofibroblasts from mouse and human esophagus. Gargus M, Niu C, Shaker A. J Vis Exp. 2015 Jan 18;(95):52215. doi: 10.3791/52215. PMID:25650889
10. Epimorphin(-/-) mice are protected, in part, from acute colitis via decreased interleukin 6 signaling. Shaker A, Gargus M, Fink J, Binkley J, Darwech I, Swietlicki E, Levin MS, Rubin DC. Transl Res. 2014 Jul;164(1):70-83. doi: 10.1016/j.trsl.2014.03.007. Epub 2014 Mar 25. PMID: 24731292
11. Multiple rapid swallow responses during esophageal high-resolution manometry reflect esophageal body peristaltic reserve. Shaker A, Stoikes N, Drapekin J, Kushnir V, Brunt LM, Gyawali CP. Am J Gastroenterol. 2013 Nov;108(11):1706-12. doi: 10.1038/ajg.2013.289. Epub 2013 Sep 10. PMID: 24019081
12. Epimorphin deletion inhibits polyposis in the Apcmin/+ mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion.Swietlicki EA, Bala S, Lu J, Shaker A, Kularatna G, Levin MS, Rubin DC.Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15;305(8):G564-72. doi: 10.1152/ajpgi.00486.2012. Epub 2013 Jul 25. PMID: 23886856
13. Stromal cells participate in the murine esophageal mucosal injury response. Shaker A, Binkley J, Darwech I, Swietlicki E, McDonald K, Newberry R, Rubin DC. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 1;304(7):G662-72. doi: 10.1152/ajpgi.00225.2012. Epub 2013 Jan 31. PMID: 23370675
14. Modeling colitis-associated cancer with azoxymethane (AOM) and dextran sulfate sodium (DSS).Thaker AI, Shaker A, Rao MS, Ciorba MA. J Vis Exp. 2012 Sep 11;(67). pii: 4100. doi: 10.3791/4100. PMID: 2299060
15. The value of multiple rapid swallows during preoperative esophageal manometry before laparoscopic antireflux surgery. Stoikes N, Drapekin J, Kushnir V, Shaker A, Brunt LM, Gyawali CP. Surg Endosc. 2012 Dec;26(12):3401-7. doi: 10.1007/s00464-012-2350-0. Epub 2012 May 31. PMID: 22648115
16. Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer. Rubin DC, Shaker A, Levin MS. Front Immunol. 2012 May 8;3:107. doi: 10.3389/fimmu.2012.00107. eCollection 2012. PMID: 22586430
17. Stem cells: One step closer to gut repair. Shaker A, Rubin DC. Nature. 2012 May 9;485(7397):181-2. doi: 10.1038/485181a. No abstract available. PMID: 22575955
18. Intestinal stem cells and epithelial-mesenchymal interactions in the crypt and stem cell niche. Shaker A, Rubin DC. Transl Res. 2010 Sep;156(3):180-7. doi: 10.1016/j.trsl.2010.06.003. Epub 2010 Jul 3. Review. PMID: 20801415
19. Epimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion. Shaker A, Swietlicki EA, Wang L, Jiang S, Onal B, Bala S, DeSchryver K, Newberry R, Levin MS, Rubin DC. J Clin Invest. 2010 Jun;120(6):2081-93. doi: 10.1172/JCI40676. Epub 2010 May 10. PMID: 20458144
20. Miriam Hospital morbidity and mortality conference, a case of chronic headaches. Shaker A, Snyder JE. Med Health R I. 2004 Sep;87(9):280-3. No abstract available. PMID: 15503887