Research in the Tran lab focuses on utilizing life science and cancer immunotherapy techniques to understand the molecular mechanism of how cancer develops, progresses, and resists treatments through an integrated approach from clinical observations to computational biology, and to animal models and quantitative molecular validation, with the ultimate goal of returning to human patients to develop novel, safe and effective anti-cancer therapeutics. The Tran research lab is supported by two divisions – Computational Data Science led by Son Le, Ph.D. and Harshit Manektalia, M.S.; and Experimental Biology led by Dongjiang Chen M.D., M.S., Tianyi Liu, M.D., Adam O’Dell, M.S., Samuel Amponsah-Effah, Ph.D. Student, and Karolina Warzecha, Ph.D. Student.