Publication

2022

Li Shen, Guang-Wei Zhang, Can Tao, Michelle Seo, Nicole Zhang, Junxiang J. Huang, Li Zhang, Huizhong Tao. A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning. Nature Communication. 2022 link to the paper

2021

Guang-Wei Zhang, Li Shen, Can Tao, Bo Jung, A-Hyun, Peng, Zhong Li, Li Zhang, Huizhong Tao. Medial preoptic area antagonistically mediates stress-induced anxiety and parental behavior. Nature Neuroscience. 2021 link to the paper  Featured by Nature Neuroscience News and Views link

Li Zhong, Jin-Xing Wei, Guang-Wei Zhang, Junxiang J. Huang, Brian Zingg, Xiyue Wang, Huizhong W. Tao, Li I. Zhang. Corticostriatal control of defense behavior in mice induced by auditory looming cues. Nature Communication. 2021 link to the paper

2019

Qi Fang, Xiao-lin Chou, Bo Peng, Wen Zhong, Li I. Zhang, Huizhong Whit Tao. A Differential Circuit via Retino-Colliculo-Pulvinar Pathway Enhances Feature Selectivity in Visual Cortex through Surround Suppression. Neuron. 2019 link to the paper

Guang-Wei Zhang, Li Shen, Zhong Li, Huizhong Whit Tao, Li I. Zhang. Track-Control, an automatic video-based real-time closed-loop behavior control toolbox. Biorxiv. 2019 link to the paper

2018

Guang-Wei Zhang, Li Shen, Wen Zhong, Ying Xiong, Li I. Zhang, Huizhong Whit Tao. Transforming Sensory Cues into Aversive Emotion via Septal-Habenula Pathways.  Neuron. 2018  link to the paper

Xiao-lin Chou, Xi-yue Wang, Zheng-gang Zhang, Li Shen, Brian Zingg, Jun-xiang Huang, Wen Zhong, Lukas Mesik, Li I. Zhang, Huizhong Whit Tao. Inhibitory Gain Modulation of Defense Behaviors by Zona Incerta. Nature Communications. 2018 link to the paper

Guang-Wei Zhang, Wen-Jian Sun, Brian Zingg, Li Shen, Jufang He, Ying Xiong, Huizhong Whit Tao, Li I. Zhang. A Non-canonical Reticular-Limbic Central Auditory Pathway via Medial Septum Contributes to Fear Conditioning. Neuron. 2018 link to the paper

Leena A Lbrahim, Junxiang J Huang, Sheng-zhi Wang, Young J Kim, Li I Zhang, Huizhong W Tao. Sparse Labeling and Neural Tracing in Brain Circuits by STARS Strategy: Revealing Morphological Development of Type II Spiral Ganglion Neurons. Cerebral Cortex, 2018 link to the paper

Feixue Liang, Haifu Li, Xiao-lin Chou, Mu Zhou, Nicole K Zhang, Zhongju Xiao, Ke K Zhang, Huizhong Whit Tao, Li I. Zhang. Sparse Representation in Awake Auditory Cortex: Cell-type Dependence, Synaptic Mechanism, Developmental Emergence, and Modulation. Cerebral Cortex, 2018 link to the paper

Miao Jing, …Lukas Mesik,…Li I Zhang, ….Julius Zhu, Yulong Li. A Genetically Encoded Fluorescent Acetylcholine Indicator for In Vitro and In Vivo Studies. Nature Biotechnology 2018 link to the paper.

Haifu Li, Feixue Liang, Wen Zhong, Linqing Yan, Lucas Mesik, Zhongju Xiao, Huizhong Whit Tao, Li I. Zhang. Synaptic Mechanism for Bandwidth Tuning in Awake Mouse Primary Auditory Cortex. Cerebral Cortex, 2018 Link to the paper

Brian Zingg, Hong-Wei Dong, Huizhong Whit Tao, Li I. Zhang. Input-output organization of the mouse claustrum. The Journal of Comparative Neurobiology, 2018 link to the paper

 

2017

Brian Zingg, Xiaolin Chou, Zhengang Zhang, Lukas Mesik,Feixue Liang, Huizhong Tao, Li I. Zhang. AAV-Mediated Anterograde Transsynaptic Tagging: Mapping Corticocollicular Input-Defined Neural Pathways for Defense Behaviors. Neuron. 2017. (F1000) link to the paper

Cover Article

F1000 Recommendation

 

Can Tao, Guang-Wei Zhang, Chang Zhou, Lijuan Wang, Sumei Yan, Huizhong Whit Tao, Li I. Zhang, Yi Zhou, Ying Xiong. Diversity in Excitation-Inhibition Mismatch Underlies Local Functional Heterogeneity in the Rat Auditory Cortex. Cell Rep. 2017 link to the paper

Ya-Tang Li, Qi Fang, Li I. Zhang, Huizhong Whit Tao. Spatial Asymmetry and Short-Term Suppression Underlie Direction Selectivity of Synaptic Excitation in the Mouse Visual Cortex. Cereb Cortex. 2017 link to the paper

2016

Leena Ali Ibrahim, Lukas Mesik, Xuying Ji, Ya-Tang Li, Brian Zingg, Li I. Zhang, Huizhong Whit Tao. Cross-modality Sharpening of Visual Cortical Processing through Layer-1 Mediated Inhibition.  Neuron 2016 link to the paper

Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI.Dcc Mediates Functional Assembly of Peripheral Auditory Circuits. Sci Rep. 2016 link to the paper

Can Tao, Guang-Wei Zhang, Chang Zhou, Lijuan Wang, Sumei Yan, Zhang LI, Zhou Y, Xiong Y. Synaptic Basis for the Generation of Response Variation in Auditory Cortex. Sci Rep.2016 link to the paper

Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI,Allayee H, Lusis AJ, Ohyama T, Friedman RA. Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice.  J Assoc Res Otolaryngol. 2016 link to the paper

2015

Zhou, M., Li, Y.T., Yuan, W., Tao, H.W., Zhang, L.I.Synaptic mechanisms for generating temporal diversity of auditory representation in the dorsal cochlear nucleus. Neurophysiol.  113:1358-1368 (2015). Epub 2014 Dec 4.

Liang,F., Xiong, XR., Zingg, B., Ji, X., Ibrahim, LA., Zhang, LI.*, Tao, HW*. Sensory Cortical Control of a Light Induced Arrest Behavior via Corticotectal Projections. Neuron May 6;86(3):755-67. doi: 10.1016 (2015). link to the paper

Xiong, XR., Liang,F., Zingg, B., Ji, X., Ibrahim, LA., Tao, HW., Zhang, LI., Auditory Cortex Controls Sound-driven Innate Defense Behavior through Corticofugal Projections to Inferior Colliculus. Nature Communication, Jun 11;6:7224. doi: 10.1038 (2015). link to the paper

Ji, X., Mesik, L., Xiao, Z., Zhang, LI.,Tao, HW. Thalamocortical Innervation Pattern in Mouse Auditory and Visual Cortex:  Laminar and Cell-Type Specificity. Cerebral Cortex May 15. pii: bhv099. [Epub ahead of print] (2015).

Mesik, L., Ma,WP., Li, LY., Ibrahim, LA., Huang, ZJ., Zhang, LI., Tao, HW. Functional Response Properties of VIP-expressing Inhibitory Neurons in Mouse Visual and Auditory Cortex. Neural Circuits(2015, in press)

Li, YT., Liu, BH., Chou, XL., Zhang, LI., Tao, HW. Synaptic Basis for Differential Orientation Selectivity between Complex and Simple Cells in Mouse Visual Cortex. J Neurosci.35(31):11081-93. (2015).

Kim, YJ., Ibrahim, LA., Wang, SZ., Evgrafov, OV., Knowles, JA., Wang, K., Tao,HW., Zhang, LI. EphA7 Regulates Spiral Ganglion Innervation of Cochlear Hair Cells. Neurobio.Jul 16. doi: 10.1002/dneu.22326. [Epub ahead of print] (2015)

2014

Li LY, Xiong XR, Ibrahim LA, Yuan W, Tao HW, Zhang LI. Differential Receptive Field Properties of Parvalbumin and Somatostatin Inhibitory Neurons in Mouse Auditory Cortex.  Cereb Cortex.2014 Jan 14. [Epub ahead of print]

Li YT, Liu BH, Zhang LI,Tao HW. Strengthening of Direction Selectivity by Broadly Tuned and Spatiotemporally Offset Inhibition in Mouse Visual Cortex. Cereb Cortex.2014 Mar 20. [Epub ahead of print]

Zhou M, Liang FL, Xiong XR, Li L, Li H, Xiao Z, Tao HW, Zhang LI.Laminar-specific Scaling Down of Balanced Excitation and inhibition in Auditory Cortex by Active Behavioral States. Nature Neuroscience, 2014 Apr 20. [Epub ahead of print]

Mark Albers; Grover Gilmore; Jeffrey Kaye; Claire Murphy; Arthur Wingfield; David Bennett; Adam Boxer; Aron Buchman; Karen Cruickshanks; Davangere P Devanand; Charles J Duffy; Christine M Gall; George A Gates; Ann-Charlotte Granholm; Takao Hensch; Roee Holtzer; Bradley T Hyman; Frank R Lin; Ann C McKee; John C Morris; Ronald C Petersen; Lisa C Silbert; Robert C Struble; John Q Trojanowski; Joe Verghese; Donald Wilson; Shunbin Xu; Li I Zhang. At the interface of sensory and motor dysfunctions and Alzheimer’s Disease.  Alzheimer’s & Dementia, (accepted 2014; authors listed alphabetically), review.

Li, L.Y., Ji, X.Y., Liang, F., Li, Y.T., Xiao, Z., Tao, H.W., Zhang, L.I.A feedforward inhibitory circuit mediates lateral refinement of sensory representation in upper layer 2/3 of mouse primary auditory cortex. Neurosci.34:13670-13683 (2014).

Tao, H.W., Li, Y.T., Zhang, L.I.Formation of excitation-inhibition balance: inhibition listens and changes its tune. Trends Neurosci.37:528-530 (2014).

Liang, F., Bai, L., Tao, H.W., Zhang, L.I.,Xiao, Z. Thresholding of auditory cortical representation by background noise.  Neural Circuits.  Nov 10;8:133. doi: 10.3389/fncir.2014.00133. eCollection (2014).

Yarong Liu, Young Joo Kim, Man Ji, Jinxu Fang, Natnaree Siriwon, Li I Zhang, and Pin Wang. Enhancing gene delivery of adeno-associated viruses by cell-permeable peptides. Molecular Therapy— Methods & Clinical Development (2014) 1, 12; doi:10.1038/mtm.2013.12

2013

Sun, Y.J., Ibrahim, L.A., Tao, H.W., &Zhang, L.I. Synaptic mechanisms underlying functional dichotomy between intrinsic-bursting and regular-spiking neurons in auditory cortical layer 5.  J Neurosci.33, 5326-39 (2013).

Wang, S.Z., Ibrahim, L.A., Kim, Y.J., Gibson, D.A., Leung, H.C., Yuan, W., Zhang, K.K. Tao, H.W., Ma, L., and Zhang, L.I. Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation. Neurosci.33(30):12242-54, (2013).

Xiong, X.R., Liang, F., Li, H., Mesik, L., Zhang, K.K., Polley, D.B., Tao, H.W., Xiao, Z., and Zhang, L.I.Interaural level difference dependent gain control and synaptic scaling underlying binaural computation. 79(4):738-53, (2013).

Li, Y.T., Ibrahim, L.A., Zhang, L.I., and Tao, H.W. Linear transformation of thalamocortical input by intracortical excitation. Nature Neuroscience16(9):1324-30, (2013).

Li, L., Li, Y.T., Zhou, M., Tao, H.W., and Zhang, L.I. Intracortical multiplication of thalamocortical signals in mouse auditory cortex.  Nature Neuroscience16(9):1179-81, (2013).

2012

Chong, S.Y., et al. Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent ofoligodendrocyte myelination. Proc Natl Acad Sci U S A.109,1299-304 (2012).

Li, Y-t., Ma, W.P., Pan, C-j., Zhang, L.I.& Tao, H.W. Broadening of Cortical Inhibition Mediates Developmental Sharpening of Orientation Selectivity.  J Neurosci. 32, 3981-91 (2012).

Zhou, Y., Mesik, L., Sun, Y.J.,Liang, F., Xiao, Z., Tao, H.W., & Zhang, L.I.Generation of Spike Latency Tuning by Thalamocortical Circuits in Auditory Cortex. J Neurosci.32, 9969-80 (2012)

Zhou M, Tao HW, & Zhang, L.I.Generation of intensity selectivity by differential synaptic tuning: fast-saturating excitation but slow-saturating inhibition. J Neurosci.32, 18068-78 (2012).

2011

Wu, G.K., Tao, H.W., & Zhang, L.I.  From elementary synaptic circuitry to information processing in primary auditory cortex.  Neuroscience & Biobehavioral Reviews.  35, 2094-104 (2011) Review

Liu BH, Ya-tang Li, Chen-Jie Pan, Li I. Zhang, Huizhong Whit Tao. Broad Inhibition Sharpens Orientation Selectivity by Expanding Excitatory Dynamic Range in Mouse Simple Cells. Neuron, 71, 542-54 (2011).

Zhang, L.I., Zhou, Y., & Tao, H.W. Perspectives on: information and coding in mammalian sensory physiology: inhibitory synaptic mechanisms underlying functional diversity in auditory cortex.  General Physiology.  138(3):311-20. (2011) Review

2010

Liu, B-h., Li, P., Li, Y-t., Sun, Y., Zhang, L.I.*, & Tao, H.W*.Intervening inhibition specifies receptive field structure in visual cortex. Nature Neurosci. (2010)..

Zhou, Y., Liu, B.H., Wu, G.K., Xiao, Z., Tao, H.W., & Zhang, L.I.  Preceding inhibition silences layer 6 neurons in auditory cortex.  Neuron65, 1-12, (2010).

Sun, Y., Wu, G.K., Liu, B.h., Li, P., Zhou, M., Xiao, Z., Tao, H.W., & Zhang, L.I. Fine-tuning of pre-balanced excitation and inhibition during auditory cortical development.  Nature465,927-931(2010).

Ma WP, Liu BH, Li YT, Huang ZJ, Zhang LI,& Tao HW. Visual representations by cortical somatostatin inhibitory neurons–selective but with weak and delayed responses. J Neurosci.  30(43):14371-9 (2010).

2009

Wang, S.Z., Liu, B.H., Tao, H.W., Xia, K, & Zhang, L.I.A genetic strategy for stochastic gene activation with regulated sparseness (STARS). PLoS ONE4(1):e4200 (2009).

Liu, B-h., Li, P., Li, Y-t., Sun, Y.J., Yanagawa, Y., Obata, K., Zhang, L.I., & Tao, H.W.Visual receptive field structure of cortical inhibitory neurons revealed by two-photon imaging guided recording.  Neurosci.  29:10520-32 (2009).

2008

Wu, G.K., Arbuckle, R., Liu, B.H., Tao, H.W., & Zhang, L.I. Lateral sharpening of cortical frequency tuning by approximately balanced inhibition.  Neuron58, 132-143 (2008).

2007

Liu, Y., Zhang, L.I.& Tao, H. Heterosynaptic scaling of developing GABAergic synapses: Dependence on glutamatergic input and developmental stage.   Neurosci. 27, 5301-12 (2007).

Liu, B.H., Wu, G.K., Arbuckle, R., Tao, H.W., & Zhang, L.I. Defining cortical frequency tuning with recurrent excitatory circuitry.  Nature Neurosci.10, 1594-600 (2007).

2006

Wu, G.Y., Li, P., Tao, H.W. & Zhang, L.I. Nonmonotonic synaptic excitation and imbalanced inhibition underlying cortical intensity tuning.  Neuron52:705-15 (2006).

2004

Nakahara, H., Zhang, L.I.and Merzenich, M.M.Specialization of primary auditory cortex processing by sound exposure in the critical period.  Natl. Acad. Sci. USA.101, 7170-4 (2004).

Tan, A.Y.Y*., Zhang, L.I.*, Merzenich, M.M. and Schreiner, C.E.Tone-driven excitatory and inhibitory synaptic conductances of primary auditory cortex neurons.  Neurophysiol.92, 630-43 (2004).

2003

Bao, S., Chan, V.T., Zhang, L.I.and Merzenich, M.M. Suppression of cortical representation through backward conditioning. Natl. Acad. Sci. USA. 100, 1405-8 (2003).

Zhang, L.I.*, Tan, A.Y.Y.*, Schreiner, C.E. and Merzenich, M.M. Topography and synaptic shaping of direction selectivity in auditory cortex. Nature424, 201-5 (2003).

2002

Engert, F., Tao, H.W., Zhang, L.I.and  Poo, M.-m.  Moving visual stimuli induce direction-sensitive responses of developing tectal neurons.  Nature419, 470-475 (2002).

Zhang, L.I., Bao, S. and Merzenich, M.M. Disruption of primary auditory cortex by synchronous auditory inputs during a critical period. Natl. Acad. Sci. USA.99, 2309-14 (2002).

2001

Tao, H.W., Zhang, L.I., Engert, F. and Poo M. Emergence of input specificity of LTP during development of retinotectal connections in vivo. Neuron31, 569-80 (2001).

Zhang, L.I., Bao, S. and Merzenich, M.M. Persistent and specific influences of early acoustic environments on primary auditory cortex.  Nature Neurosci.4, 1123-30 (2001).

Zhang, L.I.and Poo, M.-m. Electrical activity and development of neural circuits. Nature Neurosci.4 Suppl., 1207-14 (2001).  (peer reviewed Review Article)

2000

Tao, H.-z.W., Zhang, L.I., Bi, G.-q. and Poo, M.-m. Selective presynaptic propagation of LTP in defined neural networks. Neurosci.20, 3233-43 (2000).

Zhang, L.I., Tao, H.-z.W., and Poo, M.-m.Modification of developing retinotectal synapses by repetitive visual stimulation. Nature Neurosci.3, 708-15 (2000).

1998

 

Zhang, L.I.,Tao, H.-z.W., Holt, C.E., Harris, W.A. and Poo, M.-m. A critical window for cooperation and competition among developing retinotectal synapses. Nature(leading article) 395, 37-44 (1998).