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Services

  • Consultation on study design and implementation for research incorporating molecular genomic technologies or methodologies, including consultation for single cell profiling and spatial transcriptomics.
  • Sample preparation to improve success: compromised blood samples, blood spots, FFPE, fresh frozen specimens, live tissue/cells for single cell profiling, and plasma for cell free nucleic acid profiling. Lab automation systems enable high throughput sample preparation and analyte extraction (including FFPE).
  • Genotyping: RT-PCR, Microarray SNP genotyping, including Q-PCR (QuantStudio 7) for higher quality data.
  • Next Gen. Sequencing: Targeted, whole exome, whole genome bulk sequencing, mRNA-seq and whole transcriptome bulk sequencing, including access to Illumina NovaSeq6000 for high throughput sequencing.
  • Single Cell and Spatial Profiling: single cell DNA and RNA profiling capabilities, and Spatial RNA profiling.
  • Epigenomics: microarray DNA methylation, targeted DNA methylation by NGS, whole genome bisulfite sequencing, ChIP-seq by NGS, ATAC-seq by NGS, single cell ATAC-seq.
  • CLIA sequencing services include: clinically-validated targeted tumor sequencing for pediatric cancers.
  • Bioinformatic and analytic services (with the Data Science Core).
  • Centralized access and ordering of primers from IDT, and Sanger sequencing from Genewiz.
  • Training for USC Norris faculty and trainees on technology assays, and biomedical informatics tools
University of Southern California