Projects

Southern California Evidence Review Center Projects and Publications

2023

Funding Agency Project Topic


Journal Articles and Evidence Reports

USC/CHLA Cell Therapy Program CAR-T Gene Therapy Elsallab M, Ellithi M, Hempel S, Abdel-Azim H, & Abou-el-Enein M (2023). Long-term response to Autologous Anti CD19 Chimeric Antigen Receptor T cells in Relapsed or Refractory B cell Acute Lymphoblastic Leukemia: A Systematic Review and Meta-analysis. Cancer Gene Therapy.
AHRQ EPC Program TO1 Methods and Dissemination

Morgan R, Yepes-Nuñez J, Ewusie J, Mbuagbaw L, Chang S, Baldeh T, Hempel S, Helfand M, Shekelle P, Wilt T, Schünemann H. (2022). Improving GRADE Evidence Tables Part 4: A Three-Arm Non-Inferiority Randomized Trial Demonstrates Improved Understanding of Content in Summary of Findings Tables with a New Format. Journal of Clinical Epidemiology; 2022 Dec 8;S0895-4356(22)00317-1.

Chou R, Baker WL, Banez LL, Iyer S, Myers ER, Newberry S, Pincock L, Robinson KA, Sardenga L, Sathe N, Springs S, Wilt TJ. Agency for Healthcare Research and Quality Evidence-based Practice Center methods provide guidance on prioritization and selection of harms in systematic reviewsJ Clin Epidemiol. Jun 2018;98:98-104. PMID: 29409913

Yepes-Nunez JJ, Morgan RL, Mbuagbaw L, Carrasco-Labra A, Chang S, Hempel S, Shekelle P, Helfand M, Baldeh T, Schunemann HJ. Two alternatives versus the standard Grading of Recommendations Assessment, Development and Evaluation (GRADE) summary of findings (SoF) tables to improve understanding in the presentation of systematic review results: a three-arm, randomised, controlled, non-inferiority trialBMJ Open. Jan 23 2018;8(1):e015623. PMID: 29362242

Tricco AC, Lillie E, Zarin W, O’Brien KK, Colquhoun H, Levac D, Moher D, Peters MDJ, Horsley T, Weeks L, Hempel S, Akl EA, Chang C, McGowan J, Stewart L, Hartling L, Aldcroft A, Wilson MG, Garritty C, Lewin S, Godfrey CM, Macdonald MT, Langlois EV, Soares-Weiser K, Moriarty J, Clifford T, Tuncalp O, Straus SE. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and ExplanationAnn Intern Med. Oct 2 2018;169(7):467-473. PMID: 30178033

Mitchell MD, White CM, Guise J-M, Bañez L, Umscheid C, Hartling L, Lyer S, Borsky A, Berkman N, Robinson K, Newberry S, Fiordalisi C, Henderson J, Sandlers-Schmidler G. How Do Health System Leaders Use Evidence To Inform Action? International Journal of Technology Assessment in Health Care. 2018;34(S1):74-75.

Lin JS, Rubenstein LV, Beil TL, Hempel S. Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test of an Interactive, Web-Based Presentation and Discussion of Evidence. Rockville (MD); 2018.

AHRQ Disparities and Barriers for Pediatric Cancer Survivorship Care Mobley E, Moke D, Milam J, Ochoa-Dominguez C, Stal J, Mitchell H, Aminzadeh N, Bolshakova M, Mailhot Vega R, Dinalo J, Motala A, Hempel S (2023). Disparities in Pediatric Cancer Survivorship Care: A Systematic Review. Cancer Medicine. https://onlinelibrary.wiley.com/doi/10.1002/cam4.6426
Psychological Health Center of Excellence Systematic Reviews of Psychological Health Research to Address Gaps in Practice II

Gore K, Chen C, Fu N, Larkin J, Motala A, Hempel S (2023). Interventions for People Who Have Attempted Suicide and Their Family Members: A Systematic Review. Santa Monica, CA: RAND Corporation, 2023.

2022

Funding Agency Project Topic Journal Articles and Evidence Reports
USC, Population and Public Health Science Primary care cancer survivorship care Stal J, Piombo S, Kagramanov D, Mishra A, Kysh L, Freyer D, Turner B, Hempel S, Miller K (2022). The integration of primary care and childhood cancer survivorship care: A scoping review. Journal of Cancer Survivorship, 2022
International AIDS Society HIV/AIDS Stigma and Discrimination Ferguson L, Gruskin S, Bolshakova M, Fu N, Cabrer N, Rozelle M, Kasoka K, Oraro T, Stackpool-Moore L, Motala A, Hempel S (2022). Frameworks and Measures for HIV-Related Internalized Stigma, Stigma and Discrimination in Healthcare and in Laws and Policies: A Systematic Review. Journal of the International AIDS Society, 25(S1):e25915.

Hempel S, Ferguson L, Bolshakova M, Yagyu S, Fu N, Motala A, Gruskin S (2021). Frameworks, measures, and interventions for HIV-related internalized stigma and stigma in healthcare and laws and policies: Systematic review protocolBMJ Open

Hempel S, Ferguson L, Fu N, Christie N, Yagyu S, Bolshakova M, Rozelle M, Motala A, Gruskin S. Knowledge syntheses of stigma: A needed umbrella review. 24th International AIDS Conference, July 29 to August 2, 2022, Montreal, Canada.

Ferguson L, Gruskin S, Bolshakova M, Yagyu S, Fu N, Cabrera N, Rozelle M, Kasoka K, Oraro-Lawrence T, Stackpool-Moore L, Motala A, Hempel S. Frameworks and Measures for HIV-Related Internalized Stigma, Stigma and Discrimination in Healthcare and in Laws and Policies: A Systematic Review. 24th International AIDS Conference, July 29 to August 2, 2022, Montreal, Canada.

Ferguson L, Hempel S, Oraro-Lawrence T, Kasoka K, Stackpool-Moore L, Gruskin S. Interventions to Address HIV-Related Internalized Stigma, Stigma and Discrimination in Healthcare, and in Laws and Policies: A Systematic Review. 24th International AIDS Conference, July 29 to August 2, 2022, Montreal, Canada.

Susanne Hempel, Laura Ferguson, Maria Bolshakova, Sachi Yagyu, Aneesa Motala, Sofia Gruskin. Getting to the Heart of Stigma: Systematic Review Protocol. PROSPERO 2021 CRD42021249348.

Psychological Health Center of Excellence Systematic Reviews of Psychological Health Research to Address Gaps in Practice I

Apaydin E, Delavale V, Fu N, Larkin J, Chough I, Motala A, Hempel S (2022). Programs for Care System Transitions in Mental Health: A Systematic Review. RAND Research Report RRA119-4. Santa Monica, CA: RAND Corporation.

Wong E, Ruelaz Maher A, Motala A, Ross R, Danz M, Akinniranye O, Larkin J & Hempel S (2021). Methods for Identifying Health Research Gaps, Needs, and Priorities: A Scoping Review. Santa Monica, CA: RAND Corporation, 2021.

Grant S, Azhar A, Han E, Booth M. Motala A, Larkin J, Hempel S. (2021). Clinical interventions for adults with comorbid alcohol use and depressive disorders: A systematic review and network meta-analysis. PLOS Medicine.

Gore K, Newberry S, Hempel S (2020). Do we know how to treat alcohol misuse in women? RAND Blog April 2020

Gore K, Belsher B, & Hempel S (2020). Steps for Identifying Psychological Health Evidence Synthesis Topics: Gap analysis, research prioritization, and synthesis need identification. SAGE Research Methods Cases Medicine & Health

Newberry, S, Booth, M, Rutter, CM, Apaydin, E, Karimi, G, Shanman, RM, Motala, A, Maglione, MA, and Hempel, S. Gender Differences in Response to Alcohol Use Disorder Treatment: A Systematic Review. Santa Monica, CA: RAND Corporation, 2019.

Newberry, S, Gore, K, Belsher, B, Bird, C, Hempel, S. Do Women and Men Respond Differently to Alcohol Use Disorder Treatment?  Front Womens Health 4

Newberry S, Rutter C, Hempel S. Gender differences in response to alcohol use disorder treatment. PROSPERO 2017 CRD42017070895

Hempel S, Gore K, Belsher B. Identifying Research Gaps and Prioritizing Psychological Health Evidence Synthesis Needs. Med Care. Oct 2019;57 Suppl 10 Suppl 3:S259-S264. PMID: 31517797

Belsher BE, Beech EH, Kelber MS, Hempel S, Evatt DP, Smolenski DJ, Campbell MS, Otto JL, Morgan MA, Workman DE, Stewart L, Morgan RL, Khusid M, Edwards-Stewart A, O’Gallagher K, Bush N. Establishing an Evidence Synthesis Capability For Psychological Health Topics in the Military Health System. Med Care. Oct 2019;57 Suppl 10 Suppl 3:S265-S271. PMID: 31517798

Maglione MA, Raaen L, Chen C, Azhar G, Shahidinia N, Shen M, Maksabedian E, Shanman RM, Newberry S, Hempel S. Effects of medication assisted treatment (MAT) for opioid use disorder on functional outcomes: A systematic review. J Subst Abuse Treat. Jun 2018;89:28-51. PMID: 29706172

Maglione M, Raaen L, Chen C, Azhar G, Shahidinia N, Shen M, Maksabedian E, Shanman R, Hempel S. Effects of Medication-Assisted Treatment (MAT) for Opioid Use Disorder on Functional Outcomes: A Systematic Review. Santa Monica, CA 2018

Newberry, S, Booth, M, Rutter, CM, Apaydin, E, Karimi, G, Shanman, RM, Motala, A, Maglione, MA, and Hempel, S. Gender Differences in Response to Alcohol Use Disorder Treatment: A Systematic Review. Santa Monica, CA: RAND Corporation, 2019.

Newberry S, Rutter C, Hempel S. Gender differences in response to alcohol use disorder treatment. PROSPERO 2017 CRD42017070895

Hempel S, Gore K, Belsher B. Identifying Research Gaps and Prioritizing Psychological Health Evidence Synthesis Needs. Med Care. Oct 2019;57 Suppl 10 Suppl 3:S259-S264. PMID: 31517797

Belsher BE, Beech EH, Kelber MS, Hempel S, Evatt DP, Smolenski DJ, Campbell MS, Otto JL, Morgan MA, Workman DE, Stewart L, Morgan RL, Khusid M, Edwards-Stewart A, O’Gallagher K, Bush N. Establishing an Evidence Synthesis Capability For Psychological Health Topics in the Military Health System. Med Care. Oct 2019;57 Suppl 10 Suppl 3:S265-S271. PMID: 31517798

Maglione MA, Raaen L, Chen C, Azhar G, Shahidinia N, Shen M, Maksabedian E, Shanman RM, Newberry S, Hempel S. Effects of medication assisted treatment (MAT) for opioid use disorder on functional outcomes: A systematic review. J Subst Abuse Treat. Jun 2018;89:28-51. PMID: 29706172

Maglione M, Raaen L, Chen C, Azhar G, Shahidinia N, Shen M, Maksabedian E, Shanman R, Hempel S. Effects of Medication-Assisted Treatment (MAT) for Opioid Use Disorder on Functional Outcomes: A Systematic Review. Santa Monica, CA 2018

Maglione M, Hempel S, Raaen L, Shanman R (2017). Effects of medication assisted treatment (MAT) for opioid use disorder on functional outcomes. PROSPERO 2017 CRD42017058608

Maglione M, Hempel S, Newberry S, Maher AR, Colaiaco B, Kandrack R, Ewing B, Shanman R, Sorbero M. Mindfulness meditation for tobacco use cessation. PROSPERO 2015 CRD42015025053

Pedersen ER, Rubenstein L, Kandrack R, Danz M, Belsher B, Motala A, Booth M, Larkin J, Hempel S. Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression. Implement Sci. Jul 20 2018;13(1):99. PMID: 30029676

Pedersen E, Kandrack R, Danz M, Motala A, Booth M, Larkin J, Hempel S. Provider Interventions to Increase Uptake of Evidence-Based Treatment for Depression: A Systematic Review. Santa Monica, CA 2018

Pedersen E, Kandrack R, Danz M, Motala A, Booth M, Larkin J, Hempel S. Provider interventions to increase uptake of evidence-based treatment for depression. ID=CRD42017060460.

Apaydin EA, Maher AR, Raaen L, Motala A, Baxi S, Shanman RM, Hempel S. The Use of Technology in the Clinical Care of Depression: An Evidence Map. J Clin Psychiatry. Aug 21 2018;79(5). PMID: 30152646

Maher AR, Hempel S, Apaydin E. The use of technology to augment clinical care in depression and anxiety disorders. PROSPERO 2017 CRD42017069691

Grant S, Larkin J, Booth M, Azhar G, Han E, Motala A, Hempel S. Interventions for adults with co-morbid alcohol use and depressive disorders: a systematic review and network meta-analysis protocol. PROSPERO 2017 CRD42017078239

Psychological Health Center of Excellence Cross-Agency Assessment of Impact of Mental Health Campaigns on Negative Perceptions About Mental Health Conditions and Treatment and Awareness of Resources

Crandall C, Danz M, Huynh D, Baxi S, Rubenstein L, Thompson G, Al-Ibrahim H, Larkin J, Motala A, Akinniranye G & Hempel S (2022). Peer-to-Peer Support Interventions for Health Care Providers: A Series of Literature Reviews. Santa Monica, CA: RAND Corporation, 2022.

Bouskill K, Danz M, Meredith L, Chen C, Chang J, Baxi S, Huynh D, Al Ibrahim H, Motala A, Larkin J, Akinniranye O, Hempel S (2022). Definitions, prevalence, risk factors, prevention, and interventions literature reviews. RAND Research Report RRA428-1. Santa Monica, CA: RAND Corporation.

Meredith LS, Bouskill K, Chang J, Larkin J, Motala A, Hempel S (2022). Predictors of burnout among US healthcare providers: a systematic review. BMJ Open, 12(8):e054243.

Bouskill K, Danz M, Meredith L, Chen C, Chang J, Baxi S, Huynh D, Al Ibrahim H, Motala A, Larkin J, Akinniranye O, Hempel S (2022). Burnout definitions, prevalence, risk factors, prevention, and interventions literature reviews. RAND Research Report RRA428-1. Santa Monica, CA: RAND Corporation.

Bouskill K, Danz M, Meredith L, Akinniranye O, Motala A, Larkin J, Hempel S (2020). A systematic review of risk factors for predicting burnout in U.S. healthcare providers. PROSPERO 2020 CRD42020148368

Crandall C, Huynh D, Danz M, Baxi S, Rubenstein L, Thompson G, Ibrahim HA, Larkin J, Motala A, Akinniranye O, Hempel S. Peer-to-peer support interventions for healthcare providers. PROSPERO 2020 CRD42020179814

Hempel S, Huynh D, Danz M, Baxi S, Rubenstein L, Thompson G, Al Ibrahim H, Larkin J, Motala A, Akinniranye O, & Crandall C (2020). Evidence map of professional peer-to-peer interventions: Protocol. Open Science Framework

Bouskill, K, Danz, M, Meredith, LS, Akinniranye, O, Motala, A, Hempel, S. Evidence Map of Burnout Interventions.

USC Master of Social Work Addressing the Homeless Crisis with Intensive Case Management Collier B, Motala A, Ta O (2022). Addressing the homeless crisis with intensive case management. CAL MATTERS
VA Quality Indicators for High Need Patients

Schneberk, T., Bolshakova, M., Sloan, K. et al. Quality Indicators for High-Need Patients: a Systematic ReviewJ GEN INTERN MED (2022).

Schneberk, T., Bolshakova, M., Sloan, K., Stal, J., Dinalo, J., Motala, A., Baluyot, D., Chang, E., and Hempel, S. Quality Indicators for High Need Patients: Systematic Review Protocol. November 29, 2020. PROSPERO registration: CRD42020215917

2021

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQ Radiation Therapy for Brain Metastases

Garsa A, Jang JK, Baxi S, Chen C, Akinniranye O, Hall O, Larkin J, Motala A, Newberry S, Hempel S (2021). Radiation Therapy for Brain Metastases. Comparative Effectiveness Review No. 242. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2015-00001-I.) AHRQ Publication No. 21-EHC021. PCORI Publication No. 2020-SR-02. Rockville, MD: Agency for Healthcare Research and Quality; June 2021. DOI: 10.23970/AHRQEPCCER242

Garsa A, Jang J, Baxi S, Chen C, Akinniranye O, Hall O, Larkin J, Motala A, Hempel S. (2021). Radiation Therapy for Brain Metastases: A Systematic ReviewPractical Radiation Oncology.

Motala A, Hempel S, Garsa A, Akinniranye G, Baxi S, Chang J, Newberry J, Larkin K, Hall O. Radiation Therapy for Brain Metastases: A Systematic Review. PROSPERO 2020 CRD42020168260

Garsa A, Baxi S, Chen C, Hall O, Larkin J, Motala A, Newberry S, Hempel S (2021). Radiation Therapy for Brain Metastases: A Systematic Review. Research Protocol. Rockville, MD: Agency for Healthcare Research and Quality; January 2020.

mHealth Technology for Stroke Survivors The Gehr Family Center for Health Systems Science and Innovation

Torriani C, Demers M, Polese J, Bishop L, Wade E; Hempel S, Winstein C (2021). Health technologies used to capture walking and arm use behavior in adult stroke survivors: a scoping review beyond measurement propertiesDisability and Rehabilitation.

Torriani-Pasin C, Demers M, Polese J C, Bishop L, Wade E, Hempel S, & Winstein C (2020). mHealth technology for capturing levels of functional movement behavior in adult stroke survivors: a scoping review protocol beyond psychometric properties. Open Science Framework:

CHEST Evaluation of Pulmonary Nodules Hempel S, Wiener R, Bolshakova M, Li J, Meador M, Yagyu S, Rozelle M, Motala A, Iaccarino J, Gould M (2021). Evaluation of Pulmonary Nodules: Systematic Review Protocol. PROSPERO 2021 CRD42021257650
The Department of Veterans Affairs Primary Care Productivity
Hempel, S., Curtis, I., Fihn, S., Brothers, A., Danz, M., Nelson, K., … Rubenstein, L. (2020, August 4). Primary Care Productivity Scoping Review.
Hempel, Susanne, Idamay Curtis, Stephan D. Fihn, Annie Brothers, Marjorie Danz, Karin M. Nelson, Aneesa Motala, and Lisa V. Rubenstein, Primary Care Productivity: Findings from the Literature and Perspectives from a Stakeholder Panel. Santa Monica, CA: RAND Corporation, 2021
AHRQ Disparities and Barriers for Pediatric Cancer Survivorship Care

Mobley EM, Moke DJ, Milam J, Ochoa CY, Stal J, Osazuwa N, Bolshakova M, Kemp J, Dinalo JE, Motala A, Baluyot D, Hempel S. Disparities and Barriers to Pediatric Cancer Survivorship Care . Technical Brief No. 39. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 75Q80120D00009.) Rockville, MD: Agency for Healthcare Research and Quality; March 2021. DOI: 10.23970/AHRQEPCTB39Link to Exit Disclaimer

Mobley E, Moke D, Milam J, Ochoa J, Stal J, Osazuwa J, Bolshakova M, Motala A, Dinalo J, Baluyot D, & Hempel S (2020). Disparities and Barriers to Pediatric Cancer Survivorship Care. OSF. July 21. doi:10.17605/

Mobley E, Moke D, Milam J, Ochoa C, Stal J, Bolshakova M, Dinalo J, Motala A, Hempel S. (2020). Disparities and Barriers for Pediatric Cancer Survivorship Care. Agency for Healthcare Research and Quality, Methods for Effective Health Care. Research protocol, published June 24, 2020

2020

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQ Safety of Vaccines Motala A, Hempel S, Gidengil C, et al. Safety of Vaccines Used for Routine Immunization in the United States: An update. PROSPERO 2020 CRD42020180089 2020. Accessed on August 10, 2020.
School of Pharmacy, USC Vitamin D on Lung Health in Cystic Fibrosis A Young Park, Paul Beringer, Jennifer Dinalo, Adupa Rao, Susanne Hempel. A systematic review of the effects of vitamin D on lung health in cystic fibrosis. PROSPERO 2020 CRD42020167256
The Gehr Family Center for Health Systems Science and Innovation  Screening for Adverse Childhood Experiences (ACEs) in a Healthcare Setting
Mishra K, Atkins D, Wu J, Gutierrez B, Cousineau M, Hempel S (2021). Screening for Adverse Childhood Experiences in Preventive Medicine settings: A scoping review. Journal of Public Health.
Mishra K, Hempel S, Cousineau M, Atkins M, Gutierrez B, Wu J (2020). Scoping Review Protocol: Screening for Adverse Childhood Experiences (ACEs) in a Healthcare Setting. Protocol. OSF August 14
AHRQ Allocation of Scarce Resources

Allocation of Scarce Resources During Pandemics: Strategies for Policy Makers. Research Protocol

Hempel S, Burke R, Hochman M, Thompson G, Brothers A, Shin J, Motala A, Bolshakova M, Fu N, Ringel J. Strategies for Policy Makers to Allocate Scarce Resources in a Pandemic. Academy Health Annual Research Meeting, June 14-17, 2021, virtual ARM. http://dx.doi.org/10.13140/RG.2.2.31056.43527

Hempel S, Burke RV, Hochman M, Thompson G, Brothers A, Shin J, Motala A, Larkin J, Ringel J. Resource Allocation and Pandemic Response: An Evidence Synthesis To Inform Decision Making. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2015-00010-I). AHRQ Publication No. 20(21)-EHC027. Rockville, MD: Agency for Healthcare Research and Quality. October 2020. Posted final reports are located on the Effective Health Care Program search page. DOI: 10.23970/COVIDRESOURCELink to Exit Disclaimer.

Hempel S, Burke R, Hochman M, Thompson G, Brothers A, Shin J, Motala A, Bolshakova M, Fu N, Ringel J. Strategies for Policy Makers to Allocate Scarce Resources in a Pandemic. Journal of Clinical Epidemiology.

VA Evidence-Based Quality Improvement as an Implementation Strategy for Evidence-Based Practices

Hempel S, Bolshakova M, Turner B, Dinalo J, Rose D, Motala A, Fu N, Clemesha C, Rubenstein L, Stockdale S (2022). Evidence-Based Quality Improvement: A Scoping Review of the LiteratureJournal of General Internal Medicine. 37, 4257–4267.

Hempel S, Bolshakova M, Turner B, Rose D, Dinalo J, Motala A, Clemensha C, Baluyot D, & Stockdale S. (2020). Scoping Review Protocol: Evidence-Based Quality Improvement as an Implementation Strategy for Evidence-Based Practices. Open Science Framework

2019

Funding Agency Project Topic Journal Articles and Evidence Reports
PCORI Infantile Epilepsy

Apaydin E, Partikian A, Rollison J, Baxi S, Fu N, Hempel S. (2021). An evidence map of treatments for infantile epilepsyEpilepsy Research.

Rollison, J., Partikian, A., Akinniranye, O., Yagyu, S., Motala, A., Hempel, S. Topic Brief: Infantile Epilepsy. Prepared by the RAND Corporation for the Patient-Centered Outcomes Research Institute (PCORI). December 2019.

PCORI Enhanced Recovery After Surgery for Vascular Surgery Rollison, J., Woo, K., Chen, C., Yagyu, S., Motala, A., Hempel, S. Topic Brief: Enhanced Recovery After Surgery for Vascular Surgery. Prepared by the RAND Corporation for the Patient-Centered Outcomes Research Institute (PCORI). November 2019.
Department of Veterans Affairs Access management

Rubenstein L, Hempel S, Danz M, Rose D, Stockdale S, Curtis I, Kirsh S. Eight Priorities for Improving Primary Care Access Management in Healthcare Organizations: Results of a Modified Delphi Stakeholder Panel. J Gen Intern Med. Nov 14 2019. PMID: 31728895

Kaboli PJ, Miake-Lye IM, Ruser C, Yano EM, Orshansky G, Rubenstein L, Curtis I, Kirsh S, Hempel S. Sequelae of an Evidence-based Approach to Management for Access to Care in the Veterans Health Administration. Med Care. Oct 2019;57 Suppl 10 Suppl 3:S213-S220. PMID: 31517790

Hempel, S, Stockdale S, Danz M, Rose D, Kirsh S, Curtis I, Rubenstein L. Access Management in Primary Care: Perspectives from an Expert Panel. Santa Monica, CA 2018.

NIH Child Health and Human Development Microsimulation of Obesity Policies

Richardson AS, Chen C, Sturm R, Azhar G, Miles J, Larkin J, Motala A, Hempel S. Obesity Prevention Interventions and Implications for Energy Balance in the United States and Mexico: A Systematic Review of the Evidence and Meta-Analysis. Obesity (Silver Spring). Sep 2019;27(9):1390-1403. PMID: 31325241

Hempel S, Richardson A, Sturm R, Raaen L, Motala A, Azhar G. Systematic review protocol for obesity prevention policies. CRD42017077083.

Department of Veterans Affairs VA ESP Program Support 2014

Giannitrapani K, Holliday J, Miake-Lye I, Hempel S, Taylor SL. Synthesizing the Strength of the Evidence of Complementary and Integrative Health Therapies for Pain. Pain Med. May 9 2019. PMID: 31070752

Martineau M & Hempel S (2018). Managing Pain with Alternative Therapies. Santa Monica, CA: RAND Corporation, Infographic Series. .

Hilton LG, Marshall NJ, Motala A, Taylor SL, Miake-Lye IM, Baxi S, Shanman RM, Solloway MR, Beroesand JM, Hempel S. Mindfulness meditation for workplace wellness: An evidence map. Work. 2019;63(2):205-218. PMID: 31156202

Hempel S, Taylor SL, Marshall NJ, Miake-Lye IM, Beroes J, Shanman R, Solloway MR, Shekelle PG (2014). Evidence Map of Mindfulness. VA-ESP Project #05-226; 2014. Washington (DC): Department of Veterans Affairs; 2014 Oct. VA Evidence-based Synthesis Program Reports.

Hempel S, Taylor SL, Solloway M, Miake-Lye IM, Beroes JM, Shanman R, Shekelle PG. (2014) Evidence Map of Tai Chi. VA-ESP Project #05-226; 2014. Washington (DC): Department of Veterans Affairs; 2014 Sep. VA Evidence-based Synthesis Program Reports.

USC, AHRQ Interacting with Autism

Interacting with Autism. Last updated January 2019.

Harris MJ, Kinder M, Shekelle PG, Croen L, Challman T. Partnership for Research & Dissemination of Evidence-Based Medicine in Autism-Final Report. Prepared for the Agency for Healthcare Research and Quality under award number R24 HS022029-01. University of Southern California February 29, 2016.

Gratome. Partnership for Research &Dissemination of Evidence-Based Medicine in Autism 

RAND Corporation. Interacting with Autism: A USC-RAND Partnership. 

PCORI DCIS

Bouskill K, Hempel S, Richardson A, Ganz PA, Baxi S, Zutshi R, Larkin J, Motala A, Miles JNV, Crandall CJ. Evidence map of ductal carcinoma in situ management options. Menopause. Nov 2019;26(11):1250-1258. PMID: 31567868

Bouskill K, Hempel S, Richardson A, Ganz P, Baxi S, Zutshi R, Larkin J, Motala A, Miles J, Crandall C (2019). Video: Evidence Map of Ductal Carcinoma In Situ (DCIS) Management Options. Menopause.  

PCORI Genetic Therapy
Apaydin E, Richardson A, Baxi S, Gildner J, Motala A, Hempel S. An evidence map of genetic therapies. 2021 PCORI Virtual Annual Meeting, PCORI, November 17-19, 2021, online meeting.
Apaydin E, Richardson A, Baxi S, Vockley J, Akinniranye O, Ross R, Larkin J, Motala A, Azhar G, Hempel S (2020). An evidence map of randomized controlled trials evaluating genetic therapies. BMJ Evidence-Based Medicine. 
Apaydin, E., Richardson, A., Baxi, S.,  Vockley, J.,  Akinniranye, O., Larkin, J., Motala, A., Hempel., S. Differences in lymphoma patients between chimeric antigen receptor T‑cell therapy trials and the general population. Clinical and Experimental Medicine.

Richardson A, Apaydin E, Baxi S, Vockley J, Akinniranye O, Larkin J, Motala A, and Hempel S. Landscape Review and Evidence Map of Gene Therapy, Part I: Adenovirus, Adeno-associated Virus, and Clustered Regularly Interspaced Short Palindromic Repeats. Patient-Centered Outcomes Research Institute (PCORI). Washington, DC. 2019

Richardson A, Apaydin E, Baxi S, Vockley J, Akinniranye O, Ross R, Larkin J, Motala A, Azhar G, and Hempel S. Landscape Review and Evidence Map of Gene Therapy, Part II: Chimeric Antigen Receptor- T cell (CAR-T), Autologous Cell, Antisense, RNA Interference (RNAi), Zinc Finger Nuclease (ZFN), Genetically Modified Oncolytic Herpes Virus. Patient-Centered Outcomes Research Institute (PCORI). Washington, DC 2019

Issue Brief. Gene Therapy in 2019: Milestones and Challenges. Patient-Centered Outcomes Research Institute (PCORI).

Apaydin E, Richardson A, Vockley G, Baxi S, Akinniranye O, Larkin J, Motala A, Hempel S (2019). Evidence map of genetic therapy interventions: Protocol

Department of Veterans Affairs Quality Improvement Toolkit Hempel S, Miake-Lye I, Brega AG, Buckhold F, 3rd, Hassell S, Nowalk MP, Rubenstein L, Schreiber K, Spector WD, Kilbourne AM, Ganz DA. Quality Improvement Toolkits: Recommendations for Development. Am J Med Qual. Jan 24 2019:1062860618822102. PMID: 30675797
Psychological Health Center of Excellence Systematic Reviews of Psychological Health Research to Address Gaps in Practice II

Maglione M, Chen C, Franco M, Gizaw M, Shahidinia N, Baxi S, Hempel S. (2022). Predictors of PTSD Treatment Retention and Response: A Systematic Review. RAND Research Report RR4191. Santa Monica, CA: RAND Corporation.

Maglione M, Chen C, Franco M, Tebeka M, Shahidinia N, Baxi S, Hempel S (2021). Effect of patient characteristics on PTSD treatment retention in veterans: A systematic review. Journal of Traumatic Stress. DOI: 10.1002/jts.22757 

Maher AR, Apaydin EA, Hilton L, Chen C, Troxel W, Hall O, Azhar G, Larkin J, Motala A, Hempel S. (2021). Sleep management in posttraumatic stress disorder: a systematic review. Sleep Medicine

Ruelaz Maher A, Apaydin E, Hilton L, Chen C, Troxel W, Hall O, Azhar G, Larkin J, Motala A, Hempel S (2021). Sleep Management in Posttraumatic Stress disorder (PTSD): A Systematic Review. Santa Monica, CA: RAND Corporation

Wong, EC, Danz, M, Ross, R, Motala, A, Akinniranye, O, Larkin, J, Hempel, S.
Methods for Identifying Research Gaps, Establishing Research Needs, and Determining Research Priorities A Scoping Review Protocol

Wong E, Maher A, Motala A, Ross R, Akinniranye O, Larkin J, Hempel S (2021). Methods for Identifying Health Research Gaps, Needs, and Priorities: A Scoping ReviewJournal of General Internal Medicine.

Wong E, Ruelaz Maher A, Motala A, Ross R, Danz M, Akinniranye O, Larkin J & Hempel S (2021). Methods for Identifying Health Research Gaps, Needs, and Priorities: A Scoping Review. Santa Monica, CA: RAND Corporation, 2021

Vaughan C, Azhar G, Chen C, Akinniranye O, Zutshi R, Ramchand R, Motala A, Larkin J, Hempel S. Interventions for people who have attempted suicide and their family members: a systematic review. PROSPERO 2018 CRD42018116997

Maher AR, Apaydin E, Troxel W, Larkin J, Azhar G, Motala A, Hempel S, Hilton L. Sleep management in posttraumatic stress disorder (PTSD): a systematic review.
PROSPERO 2018 CRD42018102200.

Maglione M, Chen C, Baxi S, Shahidinia N, Tebeka M, Franco M, Motala A, S. H. Predictors of PTSD treatment, retention and response. PROSPERO 2018 CRD42018115995

Department of Veterans Affairs Veterans Assessment and Improvement Laboratory-Patient Aligned Care Team Program – Evidence Review Workgroup

Hempel S, O’Hanlon C, Lim YW, Danz M, Larkin J, Rubenstein L. Spread tools: a systematic review of components, uptake, and effectiveness of quality improvement toolkits. Implement Sci. Aug 19 2019;14(1):83. PMID: 31426825

Hempel S, O’Hanlon C, Lim Y-W, Danz M, & Rubenstein L (2014). Spread: a systematic review of toolkits. PROSPERO CRD42014013930

Evidence review work group (2011). Advanced Access. Rapid review. DOI: 10.13140/RG.2.2.23397.45283
Evidence review work group (2011). Homelessness. Rapid review. DOI: 10.13140/RG.2.2.23436.77446

Evidence review work group (2011). Advanced Access. Rapid review. DOI: 10.13140/RG.2.2.23397.45283
Evidence review work group (2011). Homelessness. Rapid review. DOI: 10.13140/RG.2.2.23436.77446
Evidence review work group (2011). PCMH Evaluation Measures, Rapid review. DOI: 10.13140/RG.2.2.30147.66081.
Evidence review work group (2011). Patient Registries. Rapid review. DOI: 10.13140/RG.2.2.13370.44482
Evidence review work group (2011). Mental Health and PCMH. Rapid review. DOI: 10.13140/RG.2.2.26792.21764
Evidence review work group (2011). Role of Pharmacists. Rapid review. DOI: 10.13140/RG.2.2.20081.33126.
Evidence review work group (2011). Primary Care Team Functioning. Rapid review. DOI: 10.13140/RG.2.2.11692.72323.
Evidence review work group (2011). Readmissions. Rapid review. DOI: 10.13140/RG.2.2.18403.60969.
Evidence review work group (2011). Relational Coordination. Rapid review. DOI: 10.13140/RG.2.2.28469.93924.
Evidence review work group (2011). Secure Messaging. Rapid review. DOI: 10.13140/RG.2.2.24275.63520.
Evidence review work group (2011). Self-Management. Rapid review. DOI: 10.13140/RG.2.2.30986.52166.
Evidence review work group (2011). Motivational Interviewing. Rapid review. DOI: 10.13140/RG.2.2.14209.30566.
Evidence review work group (2011). Interactive communication. Rapid review. DOI: 10.13140/RG.2.2.27631.07848.
Evidence review work group (2012). Role of Nursing in Patient Centered Medical Homes (PCMH) / Patient Aligned Care Teams (PACT) – Examples from the literature. Rapid review. DOI: 10.13140/RG.2.2.20920.19201
Evidence review work group (2012). Primary Care Clinician Burnout and Large-Scale Practice Changes. Rapid review. DOI: 10.13140/RG.2.2.34341.96484.
Evidence review work group (2012). Guided Imagery. Rapid review. DOI: 10.13140/RG.2.2.12531.58407.
Evidence review work group (2012). Medication Renewal via Interactive Voice Response Systems. Rapid review. DOI: 10.13140/RG.2.2.25953.35680.
Evidence review work group (2012). Primary Care Resident Training and Quality Improvement in Mental Health. Rapid review. DOI: 10.13140/RG.2.2.19242.47043.
Evidence review work group (2013). Measuring Homelessness. Rapid review. DOI: 10.13140/RG.2.2.32664.24324.

Danz MS, Hempel S, Lim YW, Shanman R, Motala A, Stockdale S, Shekelle P, Rubenstein L. Incorporating evidence review into quality improvement: meeting the needs of innovators. BMJ Qual Saf. Nov 2013;22(11):931-939.

2018

Funding Agency Project Topic Journal Articles and Evidence Reports
National Coalition for Hospice and Palliative Care NCP Clinical Practice Guidelines for Quality Palliative Care Systematic Review

Ahluwalia SC, Chen C, Raaen L, Motala A, Walling AM, Chamberlin M, O’Hanlon C, Larkin J, Lorenz K, Akinniranye O, Hempel S. A Systematic Review in Support of the National Consensus Project Clinical Practice Guidelines for Quality Palliative Care, Fourth EditionJ Pain Symptom Manage. Dec 2018;56(6):831-870. PMID: 30391049

Ahluwalia S, Cohen C, Chamberlin M, Chen C, Hempel S, Motala A, Larkin J, O’Hanlon C, Raaen L, A. W. National consensus project clinical practice guidelines for quality palliative care systematic review, fourth editionPROSPERO 2018 CRD42018100065.

RAND Corporation. Press Release: Best Practices in Providing Palliative Care Supported by Growing Body of Evidence.

Department of Veterans Affairs VA-ESPProgram Support 2015

MacQueen IT, Maggard-Gibbons M, Capra G, Raaen L, Ulloa JG, Shekelle PG, Miake-Lye I, Beroes JM, Hempel S. Recruiting Rural Healthcare Providers Today: a Systematic Review of Training Program Success and Determinants of Geographic ChoicesJ Gen Intern Med. Feb 2018;33(2):191-199. PMID: 29181791.

Hempel, S, Maggard, M, Ulloa, J, Macqueen, I, Miake-Lye, I, Beroes, J, Shanman, R, Shekelle. P. Rural healthcare: a systematic reviewPROSPERO 2015 CRD42015025403. Feb 2018;33(2):191-199. PMID: 29181791.

Hempel S, Graham G, Fu N, Estrada E, Chen A, Miake-Lye, Miles J, Shanman R, Shekelle P, Beroes J, Wallin M (2017). A systematic review of the effects of modifiable risk factor interventions on the progression of multiple sclerosisMultiple Sclerosis Journal. Feb 1:1352458517690271. doi: 10.1177/1352458517690271.

Hempel S, Graham G, Fu N, Estrada E, Chen A, Miake-Lye I, Miles J, Shanman R, Shekelle P, Beroes J, Wallin M (2017). A systematic review of modifiable risk factors in the progression of multiple sclerosisMultiple Sclerosis Journal. Feb 1:1352458517690270. doi: 10.1177/1352458517690270.

Hempel S, Maggard Gibbons M, Ulloa JG, Macqueen I, Miake-Lye I, Beroes J, Shekelle P (2015). Rural Healthcare Workforce: A Systematic Review. VA ESP Project #05-226; 2015. Washington (DC): Department of Veterans Affairs; 2014 Oct. VA Evidence-based Synthesis Program Reports.

Hempel S, Fu, N, Estrada E, Chen A, Miake-Lye I, Beroes J, Miles JNV, Shanman R, Shekelle P (2015). Risk Factors for Multiple Sclerosis Progression: A Systematic Review. VA ESP Project #05-226; 2015. Washington (DC): Department of Veterans Affairs; 2014 Oct. VA Evidence-based Synthesis Program Reports.

Hempel, S. Estrada, E, Chen, A, Miake-Lye, I, Beroes, J, Shanman, R, Shekelle. P. Modifiable risk factors in the progression of multiple sclerosisJ Gen Intern Med. Feb 2018;33(2):191-199. PMID: 29181791.

Hempel, S. Estrada, E, Chen, A, Miake-Lye, I, Beroes, J, Shanman, R, Shekelle. P. Modifiable risk factors in the progression of multiple sclerosis.PROSPERO. J2015 CRD42015016461

Department of Veterans Affairs Access management Hempel, S, Stockdale S, Danz M, Rose D, Kirsh S, Curtis I, Rubenstein L. Access Management in Primary Care: Perspectives from an Expert Panel. Santa Monica, CA 2018.
AHRQ EPCProgram Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks

Newberry SJ, Chung M, Anderson CAM, Chen C, Fu Z, Tang A, Zhao N, Booth M, Marks J, Hollands S, Motala A, Larkin JK, Shanman R, Hempel S. Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks. Comparative Effectiveness Review No. 206. (Prepared by the RAND Southern California Evidence-based Practice Center under Contract No. 290-2015-00010-I.) AHRQ Publication No. 18-EHC009-EF. Rockville, MD: Agency for Healthcare Research and Quality; June 2018. Posted final reports are located on the Effective Health Care Program search page.

Newberry S, Hempel S, Chung M, Tang A, Anderson C, Fu Z, Zhao N, Motala A, Booth M, Marks J, Shanman R, Hollands S, Chen C, Smith P, M. T. Effects of dietary sodium and potassium intake on chronic disease outcomes and related risk factorsPROSPERO 2017 CRD42017056126

2017

Funding Agency Project Topic Journal Articles and Evidence Reports
Defense Centers of Excellence for Psychological Health and Traumatic Injury Evaluation of efficacy and comparative effectiveness of integrative medicine approaches to the prevention and treatment of psychological health conditions and traumatic brain injury in the Department of Defense

Research Brief: Systematic Reviews of Complementary and Alternative Therapies for Psychological and Behavioral Health Disorders. Santa Monica, CA: RAND Corporation, 2021.

Grant S, Colaiaco B, Motala A, Shanman R, Booth M, Sorbero M, Hempel S (2017). Mindfulness-Based Relapse Prevention for Substance Use Disorders: A Systematic Review and Meta-AnalysisJournal of Addiction Medicine, Jul 19, doi: 10.1097/ADM.0000000000000338.

Grant S, Hempel S, Colaiaco B, Motala A, Shanman R, Booth M, Dudley W, Smith P, Sorbero M (2015). Mindfulness-Based Relapse Prevention (MBRP) for Substance Use Disorders: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Maglione M, Ruelaz Maher A, Ewing B, Colaiaco B, Newberry S, Kandrack R, Shanman R, Sorbero M, Hempel S (2017). Efficacy of mindfulness meditation for smoking cessation: A systematic review and meta-analysisAddictive Behaviors 69 (2017) 27–34.

Maglione M, Hempel S, Ruelaz Maher A, Ewing B, Colaiaco B, Newberry S, Kandrack R, Shanman R, Sorbero M. (2016). Mindfulness Meditation for the Treatment of Tobacco Use: A Systematic Review. Santa Monica, CA: RAND Corporation, 2016.

Maglione, Margaret A., Susanne Hempel, Alicia Ruelaz Maher, Eric Apaydin, Brett Ewing, Lara Hilton, Lea Xenakis, Roberta M. Shanman, Sydne Newberry, Benjamin Colaiaco and Melony E. Sorbero. Mindfulness Meditation for Chronic Pain: A Systematic Review. Santa Monica, CA: RAND Corporation, 2016.

Hilton L, Hempel S, Ewing BA, Apaydin E, Xenakis L, Newberry S, Colaiaco B, Maher AR, Shanman RM, Sorbero ME, Maglione MA. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysisAnn Behav Med. Sep 22 2016. PMID: 27658913

Newberry S, Hempel S, Booth M, Ewing B, Maher A, O’Hanlon C, Sloan J, Vaughan C, Dudley W, Shanman R, Sorbero M (2015). Omega-3 Fatty Acids for Major Depressive Disorder: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Maher A, Hempel S, Apaydin E, Shanman R, Booth M, Miles J, Sorbero M (2015). St. John’s Wort for Major Depressive Disorder: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Apaydin EA, Maher AR, Shanman R, Booth MS, Miles JN, Sorbero ME, Hempel S. A systematic review of St. John’s wort for major depressive disorderSyst Rev. Sep 02 2016;5(1):148.

Grant S, Hempel S, Kandrack R, Motala A, Shanman R, Booth M, Miles J, Dudley W, Smith P, Sorbero M (2015). Needle Acupuncture for Substance Use Disorders: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Grant S, Kandrack R, Motala A, Shanman R, Booth M, Miles J, Sorbero M, Hempel S. Acupuncture for substance use disorders: A systematic review and meta-analysisDrug Alcohol Depend. Jun 01 2016;163:1-15.

Defense Centers of Excellence for Psychological Health and Traumatic Injury Extent, effectiveness and cost-effectiveness of integrative medicine approaches to the prevention and treatment of psychological health conditions and traumatic brain injury in the Department of Defense

Grant S, Colaiaco B, Motala A, Shanman R, Sorbero M, Hempel S. (2017). Needle Acupuncture for Posttraumatic Stress Disorder (PTSD): A Systematic Review. Santa Monica, CA: RAND Corporation, 2017.

Grant S, Colaiaco B, Motala A, Shanman R, Sorbero M, Hempel S (2017). Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-AnalysisJournal of Trauma & Dissociation.

Hilton L, Ruelaz Ruelaz A, Colaiaco B, Apaydin E, Sorbero M, Booth M, Shanman R, Hempel S. (2017). Meditation for Posttraumatic Stress Disorder: A Systematic Review. Santa Monica, CA: RAND Corporation, 2017.

Hilton L, Maher AR, Colaiaco B, Apaydin E, Sorbero ME, Booth M, Shanman RM, Hempel S. Meditation for Posttraumatic Stress: Systematic Review and Meta-analysisPsychol Trauma. Aug 18 2016.

Hilton L, Sorbero M, Maher A, Shanman R, Hempel S. Meditation for Posttraumatic Stress Disorder (PTSD)PROSPERO 2015 CRD42015025782.

Melony E. Sorbero, Kerry A. Reynolds, Coreen Farris, Ben Colaiaco, Susan L. Lovejoy, Christine Vaughan, Jennifer Sloan, Ryan Kandrack, Eric Apaydin and Patricia Herman, Acupuncture for Major Depressive Disorder: A Systematic Review, RR-1135-OSD, 2015.

Sorbero M, Ahluwalia S, Reynolds K, Lovejoy S, Farris C, Sloan J, Miles J, Vaughan C, Kandrack R, Apaydin E, Colaiaco B, Herman P (2015). Meditation for Depression: A Systematic Review of Mindfulness-Based Cognitive Therapy for Major Depressive Disorder. Santa Monica, CA: RAND Corporation, 2015.

National Institute for Occupational Safety and Health (NIOSH) Systematic Review Guidance Document for Occupational Safety and Health Outcomes Hempel S, Xenakis L, and Danz M. Systematic Reviews for Occupational Safety and Health Questions: Resources for Evidence Synthesis. Santa Monica, CA: RAND Corporation, 2016.

2016

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQEPCProgram Methods and Dissemination

Butler M, Epstein R, Totten A, Whitlock E, Ansari M, Damschroder L, Balk E, Bass E, Berkman N, Hempel S, Iyer S, Schoelles K, Guise JM (2017). AHRQ series on complex intervention systematic reviews—paper 3: adapting frameworks to develop protocolsJournal of Clinical Epidemiology, Jun 27. pii: S0895-4356(17)30632-7.

Hartling L, Guise J-M, Hempel S Featherstone R, Mitchell M, Motu’apuaka M, Robinson K; Schoelles K, Totten A, Whitlock E, Wilt T, Anderson J, Berliner E, Gozu A, Kato E, Paynter E, Umscheid C (2017). Fit for Purpose: perspectives on rapid reviews from end-user interviews. Syst Rev. 2017 Feb 17;6(1):32.

Hartling L, Guise JM, Hempel S, Featherstone R, Mitchell MD, Motu’apuaka ML, Robinson KA, Schoelles K, Totten A, Whitlock E, Wilt T, Anderson J, Berliner E, Gozu A, Kato E, Paynter R, Umscheid CA. EPC Methods: AHRQ End User Perspectives of Rapid Reviews. Research White Paper. (Prepared by the Scientific Resource Center under Contract No. 290-2012-00004-C.) AHRQ Publication No.16-EHC014-EF. Rockville, MD: Agency for Healthcare Research and Quality; April 2016.

McPheeters M, Butler M, Maglione M, Viswanathan M, O’Neil M, Epstein R, Anderson J, Guise JM, Gozu A, Kondo K, Chang C. Challenges in Conducting EPC Reviews of Behavior Change Interventions. Rockville (MD); 2015.

Robinson KA, Chou R, Berkman ND, Newberry SJ, Fu R, Hartling L, Dryden D, Butler M, Foisy M, Anderson J, Motu’apuaka M, Relevo R, Guise JM, Chang S. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies. Methods Guide for Effectiveness and Comparative Effectiveness Reviews. Rockville (MD); 2008.

Robinson KA, Chou R, Berkman ND, Newberry SJ, Fu R, Hartling L, Dryden D, Butler M, Foisy M, Anderson J, Motu’apuaka M, Relevo R, Guise JM, Chang S. Twelve recommendations for integrating existing systematic reviews into new reviews: EPC guidanceJ Clin Epidemiol. Aug 7 2015.

Robinson KA, Whitlock EP, O’Neil ME, Anderson JK, Hartling L, Dryden DM, Butler M, Newberry SJ, McPheeters M, Berkman ND, Lin JS, Chang S. Integration of Existing Systematic Reviews. Rockville (MD); 2014.

Robinson KA, Whitlock EP, Oneil ME, Anderson JK, Hartling L, Dryden DM, Butler M, Newberry SJ, McPheeters M, Berkman ND, Lin JS, Chang S. Integration of existing systematic reviews into new reviews: identification of guidance needsSyst Rev.2014;3:60.

Viswanathan M, Carey TS, Belinson SE, Berliner E, Chang S, Graham E, Guise JM, Ip SS, Maglione MA, McCrory D, McPheeters M, Newberry SJ, Sista P, White CM. Identifying and Managing Nonfinancial Conflicts of Interest for Systematic Reviews. Rockville (MD); 2013.

Viswanathan M, Carey TS, Belinson SE, Berliner E, Chang SM, Graham E, Guise JM, Ip S, Maglione MA, McCrory DC, McPheeters M, Newberry SJ, Sista P, White CM. A proposed approach may help systematic reviews retain needed expertise while minimizing bias from nonfinancial conflicts of interestJ Clin Epidemiol. Nov 2014;67(11):1229-1238.

Hartling, L., Hamm, M., Milne, A., Vandermeer, B., Santaguida, P.L., Ansari, M., Tsertsvadze, A., Hempel, S., Shekelle, P., Dryden, D.M. (2012). Validity and inter-rater reliability testing of quality assessment instruments. (Prepared by the University of Alberta Evidence-based Practice Center under Contract No. 290-2007-10021-I.) AHRQ Publication No. 12-EHC039-EF. Rockville, MD: Agency for Healthcare Research and Quality. March 2012.

Hartling L, Hamm MP, Milne A, Vandermeer B, Santaguida PL, Ansari M, Tsertsvadze A, Hempel S, Shekelle P, Dryden DM (2012). Testing the Risk of Bias tool showed low reliability between individual reviewers and across consensus assessments of reviewer pairsJ Clin Epidemiol.

AHRQEPCProgram Diagnosis of Celiac Disease Maglione MA, Okunogbe A, Ewing B, Grant S, Newberry SJ, Motala A, Shanman R, Mejia-Gonzalez N, Arifkhanova A, Shekelle P, Harmon G. Diagnosis of Celiac Disease. Comparative Effectiveness Review No. 162. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2012-00006-I.) AHRQ Publication No. 15-EHC032-EF. Rockville, MD: Agency for Healthcare Research and Quality. January 2016.

2015

Funding Agency Project Topic Journal Articles and Evidence Reports
Department of Veterans Affairs VA Literature Review

Hempel S, Maggard-Gibbons M, Nguyen DK, Dawes AJ, Miake-Lye I, Beroes JM, Booth MJ, Miles JN, Shanman R, Shekelle PG. (2015). Prevention of Wrong Site Surgery, Retained Surgical Items, and Surgical Fires: A Systematic ReviewVA-ESP Project #05-226; 2014. Washington (DC): Department of Veterans Affairs; 2014 Jan. VA Evidence-based Synthesis Program Reports.

Hempel S, Maggard-Gibbons M, Nguyen DK, Dawes AJ, Miake-Lye I, Beroes JM, Booth MJ, Miles JN, Shanman R, Shekelle PG. Wrong-Site Surgery, Retained Surgical Items, and Surgical Fires : A Systematic Review of Surgical Never EventsJAMA Surg. Aug 2015;150(8):796-805.

Hempel S, Taylor SL, Solloway MR, Miake-Lye IM, Beroes JM, Shanman R, Booth MJ, Siroka AM, Shekelle PG. (2014). Evidence Map of AcupunctureVA-ESP Project #05-226; 2014. Washington (DC): Department of Veterans Affairs; 2014 Jan. VA Evidence-based Synthesis Program Reports.

Taylor S, Hempel S, Solloway M, Miake-Lye I, Beroes J, Shekelle P (2014). An evidence map of the effects of acupunctureJ Altern Complement Med, 20(5): A91-2.

Defense Centers of Excellence for Psychological Health and Traumatic Injury Evaluation of efficacy and comparative effectiveness of integrative medicine approaches to the prevention and treatment of psychological health conditions and traumatic brain injury in the Department of Defense

Newberry S, Hempel S, Booth M, Ewing B, Maher A, O’Hanlon C, Sloan J, Vaughan C, Dudley W, Shanman R, Sorbero M (2015). Omega-3 Fatty Acids for Major Depressive Disorder: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Maher A, Hempel S, Apaydin E, Shanman R, Booth M, Miles J, Sorbero M (2015). St. John’s Wort for Major Depressive Disorder: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Grant S, Larkin J, Booth M, Azhar G, Han E, Motala A, Hempel S. Interventions for adults with co-morbid alcohol use and depressive disorders: a systematic review and network meta-analysis protocol. PROSPERO 2017 CRD42017078239 .

Grant S, Hempel S, Kandrack R, Motala A, Shanman R, Booth M, Miles J, Dudley W, Smith P, Sorbero M (2015). Needle Acupuncture for Substance Use Disorders: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

Grant S, Kandrack R, Motala A, Shanman R, Booth M, Miles J, Sorbero M, Hempel S. Acupuncture for substance use disorders: A systematic review and meta-analysis. Drug Alcohol Depend. Jun 1 2016;163:1-15.

Grant S, Hempel S, Colaiaco B, Motala A, Shanman R, Booth M, Dudley W, Smith P, Sorbero M (2015). Mindfulness-Based Relapse Prevention (MBRP) for Substance Use Disorders: A Systematic Review. Santa Monica, CA: RAND Corporation, 2015.

RAND, Department of Veterans Affairs, RWJ, and AHRQ Advancing the Science of Quality Improvement Hempel S, Shekelle PG, Liu JL, Sherwood Danz M, Foy R, Lim YW, Motala A, Rubenstein LV. Development of the Quality Improvement Minimum Quality Criteria Set (QI-MQCS): a tool for critical appraisal of quality improvement intervention publicationsBMJ Qual Saf. Dec 2015;24(12):796-804.
Form
Manual
FrameworkRubenstein L, Hempel S, Liu J, Danz M, Foy R, Lim YW, Motala A, Shekelle P. (2015). The Minimum Quality Criteria Set (QI-MQCS) for Critical Appraisal: Advancing the Science of Quality ImprovementImplementation Science, suppl. 1, Aug. 2015, p. A19Rubenstein, L., Danz, M., Hempel, S., Foy, R. & Shekelle, P.G. (2010). Advancing the science of continuous quality improvement: A framework for identifying, classifying and evaluating continuous quality improvement studies. Final project report. June 2010.Danz MS, Rubenstein LV, Hempel S, Foy R, Suttorp M, Farmer MM, Shekelle PG. Identifying quality improvement intervention evaluations: is consensus achievable? Qual Saf Health Care. Aug 2010;19(4):279-283.Rubenstein, L.V., Hempel, S., Farmer, M., Asch, S., Yano, E., Dougherty, D. & Shekelle, P. (2008). Finding order in heterogeneity: Types of quality improvement intervention publicationsQuality and Safety in Healthcare, 17(6), 403-8.Rubenstein, L. Hempel, S., Danz, M., Foy, R., & Shekelle, P. Final Progress Report Expert Panel Meeting Advancing the Science of Continuous Quality Improvement. Grant Award Number: 1R13HS018139-01. Prepared for AHRQ, May 2011.O’Neill SM, Hempel S, Lim YW, Danz MS, Foy R, Suttorp MJ, Shekelle PG, Rubenstein LV. Identifying continuous quality improvement publications: what makes an improvement intervention ‘CQI’? BMJ Qual Saf. Dec 2011;20(12):1011-1019.Hempel S, Rubenstein LV, Shanman RM, Foy R, Golder S, Danz M, Shekelle PG. Identifying quality improvement intervention publications – A comparison of electronic search strategiesImplement Sci. 2011;6:85.
Department of Veterans Affairs Development of tools for evidence synthesis of quality improvement for use by VA’s Quality Enhancement and Research Initiative and other VA implementation researchers.

Lokker C, McKibbon KA, Colquhoun H, Hempel S. A scoping review of classification schemes of interventions to promote and integrate evidence into practice in healthcareImplement Sci. 2015;10:27.

Colquhoun H, Leeman J, Michie S, Lokker C, Bragge P, Hempel S, McKibbon KA, Peters GJ, Stevens KR, Wilson MG, Grimshaw J. Towards a common terminology: a simplified framework of interventions to promote and integrate evidence into health practices, systems, and policiesImplement Sci. 2014;9:51.

2014

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQ EPC Program Assessment of a method to detect signals for updating systematic reviews

Shekelle PG, Motala A, Johnsen B. Assessment of a Method To Detect Signals for Updating Systematic Reviews. Research White Paper (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I). AHRQ Publication No. 14-EHC015. Rockville, MD: Agency for Healthcare Research and Quality. March 2014.

Shekelle PG, Motala A, Johnsen B, Newberry SJ. Assessment of a method to detect signals for updating systematic reviews. Syst Rev. 2014;3:13.

AHRQ EPC Program Safety of Vaccines Used for Routine Immunization of Adults (Including Pregnant Women) and Children

Maglione MA, Gidengil C, Das L, Raaen L, Smith A, Chari R, Newberry S, Hempel S, Shanman R, Perry T, Goetz MB. Safety of Vaccines Used for Routine Immunization in the United States. Evidence Report/Technology Assessment No. 215. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I.) AHRQ Publication No. 14-E002-EF. Rockville, MD: Agency for Healthcare Research and Quality; July 2014.

Maglione MA, Das, L., Raaen L, Smith A, Chari R, Newberry S, Shanman R, Perry T, Goetz MB, Gidengil C. Safety of Vaccines Used for Routine Immunization of U.S. Children: A Systematic Review. Pediatrics. 2014; 134(2): 325-37

Office of the National Coordinator (ONC) Health Information Technology: An Updated Systematic Review with a Focus on Meaningful Use Functionalities

Shekelle P.G., Jones SS, Rudin BS, Shanman R, Timmer M, Perry TR, Motala A. Health Information Technology: An Updated Systematic Review with a Focus on Meaningful Use Functionalities. (Prepared by the Southern California-RAND Evidence-based Practice Center under Contract No. HHSP23337020T). 2014. Washington, D.C., Office of the National Coordinator for Health Information Technology.

Jones SS, Rudin RS, Perry T, Shekelle PG. Health Information Technology: An Updated Systematic Review with a Focus on Meaningful Use,”Ann Intern Med 2014;160:48-54

Department of Veterans Affairs CIPRS Research-Clinical Partnership Review Ovretveit J, Hempel S, Magnabosco J, Mittman B, Rubenstein L & Ganz D. Guidance for Research-Practice Partnerships (R-PPs) and Collaborative Research. In press with Journal of Health Organization and Management. 2014. 28(1). 115-126.
AHRQ EPCProgram USAID Strength of Evidence Criteria

Shekelle PG, Maglione MA, Luoto J, Johnsen B, Perry TR. Global Health Evidence Evaluation Framework. Research White Paper (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I). AHRQ Publication No. 13-EHC008-EF. Rockville, MD: Agency for Healthcare Research and Quality. January 2013.

Luoto J, Maglione MA, Johnsen B, Chang C, E SH, Perry T, Shekelle PG. Comparison of frameworks evaluating evidence for global health interventions. PLoS Med. Jul 2013;10(7):e1001469.

Luoto J, Shekelle, PG., Maglione MA, Johnsen B, Perry T. Reporting of context and implementation in studies in global health interventions: a pilot study. May 12, 2014. Implementation Science. 9(57).

RAND Probiotics for antibiotics-associated diarrhea

Hempel, S., Newberry, S., Maher, A., Wang, Z., Miles, J., Shanman, R., Johnsen, B. & Shekelle, P. (2012). Probiotics for the prevention and treatment of antibiotic-associated diarrhea: A systematic review and meta-analysisJAMA, 307 (18), 1959-1969.

Hempel S. Editorial: Probiotics for diarrhoea. Indian J Med Res. Mar 2014;139(3):339-341.

AHRQ EPCprogram Safety of Probiotics Used to Reduce Risk and prevent or treat disease

Hempel S, Newberry S, Ruelaz A, Wang Z, Miles J, Suttorp M, Johnsen B, Shanman R, Slusser W, Fu N, Smith A, Roth E, Polak J, Motala A, Perry T, & Shekelle PG. Safety of Probiotics to Reduce Risk and Prevent or Treat Disease. Evidence Report/Technology Assessment No. 200. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I) AHRQ Publication No. 11-E007-1. Rockville, MD: Agency for Healthcare Research and Quality. April 2011

Shane, A.L., Cabana, M. D., Vidry, S., Merenstein, D., Hummelen, R. Ellis, C.L. Heimbach, J.T., Hempel, S., Lynch, S.V. Sanders, M.E. Tancredi, D.J. (2010). Guide to Designing, Conducting, Publishing, and Communicating Results of Clinical Studies Involving Probiotic Applications in Human Participants. Gut Microbes, 1(4).

2013

Funding Agency Project Topic Journal Articles and Evidence    Reports
AHRQ EPC program and VA Detection of Associations Between Trial Quality and Effect Sizes Hempel, Susanne; Miles, Jeremy NV; Booth, Marika J; Wang, Zhen; Morton,
Sally C; Shekelle, Paul G.
Risk of Bias: A Simulation Study of Power to Detect Study-Level Moderator
Effects in Meta-Analysis,
 Systematic Reviews, v. 2, no.107, Nov. 2013, 10 p.Hempel S, Miles J, Suttorp M, Wang Z, Johnsen B, Morton S, Perry, T., Valentine D,
Shekelle P. Detection of Associations between Trial Quality and Effect Sizes. Methods
Research Report. Prepared by the Southern California Evidence-based Practice Center
under Contract No. 290-2007-10062-I. AHRQ Publication No. 12-EHC010-EF. Rockville,
MD: Agency for Healthcare Research and Quality; December 2012.
AHRQ EPC Program Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m² Maglione, M., Maggard Gibbons, M., Livhits, M., Ewing, B Hu, J., Ruelaz Maher, A., Li, Z.,
Shanman, R., Perry, T., Shekelle, P.G. Comparative Effectiveness of Bariatric Surgery and
Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to
34.9 kg/m² Comparative Effectiveness Review No. 82.
 (Prepared by the Southern
CaliforniaEvidence-based Practice Center under Contract No. 290-2007-10062-I.)
AHRQ Publication No. 12(13)-EHC139-EF. Rockville, MD: Agency for Healthcare
Research and Quality. June 2013.Maggard-Gibbons M, Maglione M, Livhits M, Ewing B, Maher AR, Hu J, Li Z, Shekelle PG.
Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with
diabetes: a systematic review.
 JAMA. Jun 5 2013;309(21):2250-2261.
AHRQ EPC Program Surveillance & Identification of Triggers for Updating Systematic Reviews Newberry SJ, Ahmadzai N, Motala A, Tsertsvadze A, Maglione M, Ansari MT, Hempel S,
Tsouros S, Schneider Chafen J, Shanman R, Skidmore, B, Moher D. Shekelle, PG.
Surveillance and Identification of Signals for Updating Systematic Review:
Implementation and Early Experience.
 Methods Research Report (Prepared by the RAND
Corporation, Southern California Evidence-based Practice Center under Contract No. 290
-2007-10062-I and University of Ottawa Evidence-based Practice Center 290-2007-10059-I). AHRQ Publication No. 13-EHC088-EF. Rockville, MD:
Agency for Healthcare Research and Quality; May 2013.Ahmadzai N, Newberry SJ, Maglione MA, Tsertsvadze A, Ansari MT, Hempel S, Motala A,
Tsouros S, Schneider Chafen JJ, Shanman R, Moher D, Shekelle PG.A surveillance system to assess the need for updating systematic reviews. Syst Rev.
Nov 14 2013;2(1):104.Shekelle, PG. Motala, A, Newberry, SJ, Hempel, S, Chafen, JJ, Maglione, M, Shanman, R, Surveillance Assessment on CER 9: Percutaneous Coronary Interventions and Coronary Artery Bypass Grafting for Coronary Artery Disease (CER 9). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.)
Rockville, MD: Agency for Healthcare Research and Quality. May 2013.Chafen, JJ, Newberry, SJ, Maglione M, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 13: Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer (CER 13). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. June 2012.Chafen, JJ, Newberry, SJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG. Surveillance
Assessment on CER 17: Comparative Effectiveness of Medications To Reduce Risk of Primary Breast Cancer in Women. (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. July 2012.Maglione, M, Motala, A, Shanman, R, Chafen, JJ, Newberry, SJ, Shekelle, PG. Surveillance Assessment on CER 19: Comparative Effectiveness of Core Needle Biopsy and Open Surgical Biopsy for Diagnosis of Breast Lesions (CER 19). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. July 2012.Newberry, SJ, Chafen, JJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 23: Effectiveness of Recombinant Human Growth Hormone (rhGH)
in the Treatment of Patients with Cystic Fibrosis (CER 23). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. August 2012.Newberry, SJ, Chafen, JJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 25: Traumatic Brain Injury and Depression (CER 25). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. November 2012.Maglione, M, Motala, A, Shanman, R, Chafen, JJ, Newberry, SJ, Shekelle, PG. Surveillance Assessment on CER 26: Therapies for Children with Autism Spectrum Disorders (ASDs)
(CER 26). (Prepared by Southern California Evidence Based Practice Center under Contract
No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. October 2012.Maher, AR, Shekelle, PG, Motala, A, Chafen, JJ, Newberry, SJ, Maglione, M, Shanman, R. Surveillance Assessment on CER 28: Disease-Modifying Antirheumatic Drugs (DMARDs) in Children with Juvenile Idiopathic Arthritis (JIA) (CER 28). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. February 2013.Chafen, JJ, Newberry, SJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG.Surveillance Assessment on CER 30: Comparative Effectiveness of Pain Management Interventions for Hip Fracture (CER 30). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. October 2012. Chafen, JJ, Newberry, SJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 31: Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection (CER 31). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. October 2012. Hempel, S, Newberry, SJ, Chafen, JJ, Maglione, M, Motala, A, Larkin, J, Shekelle, PG. Surveillance Assessment on CER 32: Diagnosis and Treatment of Obstructive Sleep Apnea in Adults (CER 32). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. July 2012.Newberry, SJ, Chafen, JJ, Maglione, M, Motala, A, Larkin, J, Shekelle, PG. Surveillance Assessment on CER 33: Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults (CER 33). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. August 2012.Maher, AR, Motala, A, Chafen, JJ, Newberry, SJ, Maglione, M, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 37: Chronic Kidney Disease Stages 1-3: Screening, Monitoring, and Treatment (CER 37). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. October 2012.Maglione, M, Motala, A, Larkin, JW, Chafen, JJ, Newberry, SJ, Shekelle, PG. Surveillance Assessment on CER 39: First & second generation antipsychotics for children and young adults (CER 39). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. November 2012.Hempel, S, Newberry, SJ, Chafen, JJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG.Surveillance Assessment on CER 41: Noncyclic Chronic Pelvic Pain Therapies for Women: Comparative Effectiveness (CER 41). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. October 2012.Shekelle, PG. Motala, A, Newberry, SJ, Hempel, S, Chafen, JJ, Maglione, M, Shanman, R. Surveillance Assessment on CER 42: Adjunctive Devices for Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (CER 42). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. May 2013.Maglione, M, Das, L, Motala, A, Shanman, R, Newberry, SJ, Chafen, JJ, Shekelle, PG. Surveillance Assessment on CER 44: Attention Deficit Hyperactivity Disorder (ADHD): Effectiveness of Treatment in At-Risk Preschoolers; Long-term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment (CER 44). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. July 2012.Chafen, JJ, Newberry, SJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 47: Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review (CER 47). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. January 2013.Maglione, M, Hempel, S, Newberry, SJ, Chafen, JJ, Motala, A, Shanman, R, Shekelle, PG.Surveillance Assessment on CER 50: Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in
Children (CER 50).
(Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. March 2013.Newberry, SJ, Hempel, S, Chafen, JJ, Maglione, M, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 51: Dietary Supplements in Adults Taking Cardiovascular Drugs (CER 51). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. April 2013.Maglione, M, Hempel, S, Newberry, SJ, Chafen, JJ, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 54: Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report (CER 54). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. March 2013.Maglione, M, Hempel, S, Newberry, SJ, Chafen, JJ, Motala, A, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 55: Drug Therapy for Rheumatoid Arthritis in Adults: An Update (CER 55). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. May 2013.Newberry, SJ, Chafen, JJ, Maglione, M, Motala, A, Larkin, J, Shekelle, PG. Surveillance Assessment on CER 56: Adjuvant Treatment for Phenylketonuria (CER 56). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. January 2013.Newberry, SJ, Motala, A, Hempel, S, Chafen, JJ, Maglione, M, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 59: Screening for Glaucoma: Comparative Effectiveness (CER 60). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. May 2013.Newberry, SJ, Motala, A, Hempel, S, Chafen, JJ, Maglione, M, Shanman, R, Shekelle, PG. Surveillance Assessment on CER 60: Treatment for Glaucoma: Comparative
Effectiveness (CER 60).
(Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. May 2013.Maglione, M, Motala, A, Larkin, J, Newberry, SJ, Chafen, JJ, Shekelle, PG. Surveillance Assessment on CER 62: Treatment of Depression after Unsatisfactory Response to SSRIs (CER 62). (Prepared by Southern California Evidence Based Practice Center under Contract No. 290-2007-10062I.) Rockville, MD: Agency for Healthcare Research and Quality. January 2013
AHRQ EPC Program Critical Analysis of the Evidence for Patient Safety Practices

Shekelle PG, Wachter RM, Pronovost P, Schoelles K, McDonald KM, Dy SM, et al. Making Health Care Safer II: An Updated Critical Analysis of the Evidence for Patient Safety Practices. (Prepared by the Southern California-RAND Evidence-based Practice Center under contract no. HHSA290200710062I.) Rockville, MD: Agency for Healthcare Research and Quality; March 5, 2013.

Wachter RM, Pronovost P, Shekelle P. Strategies to improve patient safety: the evidence base matures. Ann Intern Med. Mar 5 2013;158(5 Pt 1):350-352.

Shekelle PG, Pronovost PJ, Wachter RM, McDonald KM, Schoelles K, Dy SM, Shojania K, Reston JT, Adams AS, Angood PB, Bates DW, Bickman L, Carayon P, Donaldson L, Duan N, Farley DO, Greenhalgh T, Haughom JL, Lake E, Lilford R, Lohr KN, Meyer GS, Miller MR, Neuhauser DV, Ryan G, Saint S, Shortell SM, Stevens DP, Walshe K. The top patient safety strategies that can be encouraged for adoption now. Ann Intern Med. Mar 5 2013;158(5Pt 2):365-368.

Weaver SJ, Lubomksi LH, Wilson RF, Pfoh ER, Martinez KA, Dy SM. Promoting a culture of safety as a patient safety strategy: a systematic review. Ann Intern Med. Mar 5 2013;158(5 Pt 2):369-374.

Reston JT, Schoelles KM. In-facility delirium prevention programs as a patient safety
strategy: a systematic review.
 Ann Intern Med. Mar 5 2013;158(5 Pt 2):375-380.

McDonald KM, Matesic B, Contopoulos-Ioannidis DG, Lonhart J, Schmidt E, Pineda N,
Ioannidis JP. Patient safety strategies targeted at diagnostic errors: a systematic review.
Ann Intern Med. Mar 5 2013;158(5 Pt 2):381-389.

Miake-Lye IM, Hempel S, Ganz DA, Shekelle PG. Inpatient fall prevention programs as a
patient safety strategy: a systematic review.
 Ann Intern Med. Mar 5 2013;158(5 Pt 2):390-396.

Kwan JL, Lo L, Sampson M, Shojania KG. Medication reconciliation during transitions of care as a patient safety strategy: a systematic review. Ann Intern Med. Mar 5 2013;158(5 Pt 2):397-403.

Shekelle PG. Nurse-patient ratios as a patient safety strategy: a systematic review.
Ann Intern Med. Mar 5 2013;158(5 Pt 2):404-409.

Sullivan N, Schoelles KM. Preventing in-facility pressure ulcers as a patient safety strategy: a systematic review. Ann Intern Med. Mar 5 2013;158(5 Pt 2):410-416.

Winters BD, Weaver SJ, Pfoh ER, Yang T, Pham JC, Dy SM. Rapid-response systems as a
patient safety strategy: a systematic review.

Ann Intern Med. Mar 5 2013;158(5 Pt 2):417-425.

Schmidt E, Goldhaber-Fiebert SN, Ho LA, McDonald KM. Simulation exercises as a patient safety strategy: a systematic review. Ann Intern Med. Mar 5 2013;158(5 Pt 2):426-432.

Rennke S, Nguyen OK, Shoeb MH, Magan Y, Wachter RM, Ranji SR. Hospital-initiated
transitional care interventions as a patient safety strategy: a systematic review.
Ann Intern Med. Mar 5 2013;158(5 Pt 2):433-440.

Berger Z, Flickinger TE, Pfoh E, Martinez KA, Dy SM. Promoting engagement by patients
and families to reduce adverse events in acute care settings: a systematic review. BMJ Qual Saf. Jul 2014;23(7):548-555.

Carayon P, Xie A, Kianfar S. Human factors and ergonomics as a patient safety practice.
BMJ Qual Saf. Mar 2014;23(3):196-205.

Lau BD, Haut ER. Practices to prevent venous thromboembolism: a brief review. BMJ Qual Saf. Mar 2014;23(3):187-195.

Maggard-Gibbons M. The use of report cards and outcome measurements to improve the safety of surgical care: the American College of Surgeons National Surgical Quality Improvement Program. BMJ Qual Saf. Jul 2014;23(7):589-599.

Meddings J. Interventions to reduce urinary catheter use: it worked for them, but will it
work for us? BMJ Qual Saf. Dec 2013;22(12):967-971.

Ranji SR, Rennke S, Wachter RM. Computerised provider order entry combined with clinical decision support systems to improve medication safety: a narrative review. BMJ Qual Saf. Sep 2014;23(9):773-780.

Treadwell JR, Lucas S, Tsou AY. Surgical checklists: a systematic review of impacts and implementation. BMJ Qual Saf. Apr 2014;23(4):299-318.

Weaver SJ, Dy SM, Rosen MA. Team-training in healthcare: a narrative synthesis of the
literature. BMJ Qual Saf. May 2014;23(5):359-372.

2012

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQEPCProgram Machine Learning in QII Datasets Hempel S, Shetty KD, Shekelle PG, Rubenstein LV, Danz MS, Johnsen B, Dalal SR. Machine Learning Methods in Systematic Reviews: Identifying Quality Improvement Intervention Evaluations. Research White Paper (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I). AHRQ Publication No. 12-EHC125-EF. Rockville, MD: Agency for Healthcare Research and Quality. September 2012.
AHRQEPCProgram A Pilot Study using Machine Learning and Domain Knowledge to Facilitate Comparative Effectiveness Review Updating

Dalal, S.R., Shekelle, P.G., Hempel, S., Newberry, S.J., Motala, A., Shetty, K.D. Using Machine Learning to Facilitate Systematic Review Updating. Methods Research Report (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I). AHRQ Publication No. 11-EHC045-EF. Rockville, MD: Agency for Healthcare Research and Quality. September 2012.

Dalal SR, Shekelle PG, Hempel S, Newberry SJ, Motala A, Shetty KD. A pilot study using machine learning and domain knowledge to facilitate comparative effectiveness review updating. Med Decis Making. Apr 2013;33(3):343-355.

AHRQEPCProgram Allocation of Scarce Resources During Mass Casualty Events (MCEs)

Timbie JW, Ringel JS, Fox DS, Waxman DA, Pillemer F, Carey C, Moore M, Karir V, Johnson TJ, Iyer N, Hu J, Shanman R, Larkin JW, Timmer M, Motala A, Perry TR, Newberry S, Kellermann AL. Allocation of Scarce Resources During Mass Casualty Events. Evidence Report No. 207. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I.) AHRQ Publication No. 12-E006-EF. Rockville, MD: Agency for Healthcare Research and Quality. June 2012.

Timbie JW, Ringel JS, Fox DS, Pillemer F, Waxman DA, Moore M, Hansen CK, Knebel AR, Ricciardi R, Kellermann AL. Systematic review of strategies to manage and allocate scarce resources during mass casualty events. Ann Emerg Med. Jun 2013;61(6):677-689 e101.

AHRQEPCprogram Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis – An Update of the 2007 Report

Crandall CJ, Newberry SJ, Gellad WG, Diamant A, Lim YW, Suttorp M, Motala A, Ewing B, Roth B, Timmer M, Shanman R, Shekelle PG. Treatment to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis: Update of a 2007 Report. Comparative Effectiveness Review No. 53. (Prepared by Southern California Evidence-based Practice Center under Contract No. HHSA-290-2007-10062-I.) Rockville, MD: Agency for Healthcare Research and Quality; March 2012.

Crandall CJ, Newberry SJ, Diamant A, Lim YW, Gellad WG, Suttorp MJ, Motala A, Shekelle PG. Comparative Effectiveness of Pharmacological Treatments to Prevent Fractures: An Updated Systematic Review. Ann Intern Med. 2014. 161(10): 711-723.

AHRQ Review of the evidence on falls prevention in hospitals

Hempel S, Newberry S, Wang Z, Shekelle PG, Shanman R, Johnsen B, Perry T, Saliba D, Ganz DA. Review of the evidence on falls prevention in hospitals: Task 4 Final Report. AHRQ Contract No. HHSA290201000017I, PRISM No. HHSA29032001T, Task Order #1. WR-907. Santa Monica, California. RAND Corporation. February 2012.

Hempel S, Newberry S, Wang Z, Booth M, Shanman R, Johnsen B, Shier V, Saliba D, Spector WD, Ganz DA. Hospital fall prevention: a systematic review of implementation, components, adherence, and effectiveness. J Am Geriatr Soc. Apr 2013;61(4):483-494.

Hempel S, Ganz D, Shekelle P, Johnsen B, Wang Z, Newberry S, D. S. Implementation of falls prevention interventions in hospitals. Implementation of falls prevention interventions in hospitalsPROSPERO 2011 CRD42011001593.

2011

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQ EPCprogram Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics – Update

Maglione M, Ruelaz Maher A, Hu, J, Wang Z, Shanman R, Shekelle PG, Roth B, Hilton L, Suttorp MJ, Ewing BA, Motala A, Perry T. Off-Label Use of Atypical Antipsychotics Update. Evidence Report/ Technology Assessment No. 43. (Prepared by the Southern California Evidence-based Practice Center under Contract No. HHSA290200710062I). Rockville, MD: Agency for Healthcare Research and Quality. September 2011.

Ruelaz Maher, A, Maglione, M, Bagley, S, Suttorp, M, Hu, J, Ewing, B, Wang, Z, Timmer, M, Sultzer, D, Shekelle, PG. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis. JAMA. Sep 28 2011;306(12):1359-1369.

AHRQ EPCprogram Empirical evidence of associations between trial quality and effect sizes Hempel S, Suttorp MJ, Miles JNV, Wang Z, Maglione M, Morton S, Johnsen B, Valentine D, Shekelle PG. Empirical Evidence of Associations Between Trial Quality and Effect Sizes. Methods Research Report (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I). AHRQ Publication No. 11-EHC045-EF. Rockville, MD: Agency for Healthcare Research and Quality. June 2011.
AHRQ EPCprogram Identifying Signals for Updating Systematic Reviews: A Comparison of Two Methods

Shekelle PG, Newberry, SJ, Wu, H, Suttorp M, Motala, A., Lim Y-W, Balk EM, Chung, M, Yu, WW, Lee, J, Gaylor, JM, Moher, D, Ansari, MT, Skidmore, R. Garritty, C. Identifying Signals for Updating Systematic Reviews: A Comparison of Two Methods.Rockville (MD): Agency for Healthcare Research and Quality. June 2011. Methods Research Report. AHRQ Publication No. 11-EHC042-EF.

Chung M, Newberry SJ, Ansari MT, Yu WW, Wu H, Lee J, Suttorp M, Gaylor JM, Motala A, Moher D, Balk EM, Shekelle PG. Two methods provide similar signals for the need to update systematic reviews. J Clin Epidemiol. Jun 2012;65(6):660-668.

Department of Veterans Affairs Quality improvement interventions for the prevention of pressure ulcers Soban LM, Hempel S, Munjas BA, Miles J, Rubenstein LV. Preventing pressure ulcers in hospitals: A systematic review of nurse-focused quality improvement interventions. Jt Comm J Qual Patient Saf. Jun 2011;37(6):245-252.
Robert Wood Johnson Foundation, Department of Veterans Affairs Defining Continuous Quality Improvement (CQI) for Health Care Delivery

Rubenstein, L., Danz, M., Hempel, S., O’Neil, S. & Shekelle, P.G. (2011). Defining continuous quality improvement (CQI) for health care delivery. Final project report. May 2011.

Khodyakov D, Hempel S, Rubenstein L, Shekelle P, Foy R, Salem-Schatz S, O’Neill S, Danz M, Dalal S. Conducting Online Expert Panels: A Feasibility and Experimental Replicability Study. BMC Med Res Methodol. 2011 Dec 23;11(1):174.

Rubenstein L, Khodyakov D, Hempel S, Danz M, Salem-Schatz S, Foy R, O’Neill S, Dalal S, Shekelle P. How can we recognize continuous quality improvement? Int J Qual Health Care. Dec 4 2013.

CMS Outcome Measures for Medicare Hempel, S, Ganz, DA, Clifford, M, Newberry, S, Lim, Y-W, Larkin, J, Shanman, RA, Wertheimer, S, Wenger, NS, Roth, CP, Shekelle, PG. Review of the Current Literature on Outcome Measures Applicable to the Medicare Population for Use in a Quality Improvement Program. Prepared for CMS, Contact No. HHSM-500-2005-00028I. RAND Corporation. February 2011
Department of Veterans Affairs Veterans Assessment and Improvement Laboratory-Patient Aligned Care Team Program – Evidence Review Workgroup

Evidence review work group (2011). Advanced Access. Rapid review. DOI: 10.13140/RG.2.2.23397.45283.

Evidence review work group (2011). Homelessness. Rapid review. DOI: 10.13140/RG.2.2.23436.77446.

Evidence review work group (2011). PCMH Evaluation Measures, Rapid review. DOI: 10.13140/RG.2.2.30147.66081.

Evidence review work group (2011). Patient Registries. Rapid review. DOI: 10.13140/RG.2.2.13370.44482.

Evidence review work group (2011). Mental Health and PCMH. Rapid review. DOI: 10.13140/RG.2.2.26792.21764.

Evidence review work group (2011). Role of Pharmacists. Rapid review. DOI: 10.13140/RG.2.2.20081.33126.

Evidence review work group (2011). Primary Care Team Functioning. Rapid review. DOI: 10.13140/RG.2.2.11692.72323.

Evidence review work group (2011). Readmissions. Rapid review. DOI: 10.13140/RG.2.2.18403.60969.

Evidence review work group (2011). Relational Coordination. Rapid review. DOI: 10.13140/RG.2.2.28469.93924.

Evidence review work group (2011). Secure Messaging. Rapid review. DOI: 10.13140/RG.2.2.24275.63520.

Evidence review work group (2011). Self-Management. Rapid review. DOI: 10.13140/RG.2.2.30986.52166.

Evidence review work group (2011). Motivational Interviewing. Rapid review. DOI: 10.13140/RG.2.2.14209.30566.

Evidence review work group (2011). Interactive communication. Rapid review. DOI: 10.13140/RG.2.2.27631.07848.

Evidence review work group (2012). Role of Nursing in Patient Centered Medical Homes (PCMH) / Patient Aligned Care Teams (PACT) – Examples from the literature. Rapid review. DOI: 10.13140/RG.2.2.20920.19201.

Evidence review work group (2012). Primary Care Clinician Burnout and Large-Scale Practice Changes. Rapid review. DOI: 10.13140/RG.2.2.34341.96484.

Evidence review work group (2012). Guided Imagery. Rapid review. DOI: 10.13140/RG.2.2.12531.58407.

Evidence review work group (2012). Medication Renewal via Interactive Voice Response Systems. Rapid review. DOI: 10.13140/RG.2.2.25953.35680.

Evidence review work group (2012). Primary Care Resident Training and Quality Improvement in Mental Health. Rapid review. DOI: 10.13140/RG.2.2.19242.47043.

Evidence review work group (2013). Measuring Homelessness. Rapid review. DOI: 10.13140/RG.2.2.32664.24324.

Danz MS, Hempel S, Lim YW, Shanman R, Motala A, Stockdale S, Shekelle P, Rubenstein L. Incorporating evidence review into quality improvement: meeting the needs of innovators. BMJ Qual Saf. Nov 2013;22(11):931-939.

2010

Funding Agency Project Topic Journal Articles and Evidence Reports
AHRQ Developing Criteria for Context Sensitive Patient Safety Practices

Shekelle PG, Pronovost PJ, Wachter RM, Taylor SL, Carr L, Dy S, Foy R, Hempel S, McDonald K, Ovretveit J, Rubenstein L, and the PSP Technical Expert Panel. Assessing the Evidence for Context-Sensitive Effectiveness and Safety of Patient Safety Practices: Developing Criteria (Prepared under Contract No. HHSA-290-2009-10001C). AHRQ Publication No. 11-0006-EF. Rockville, MD: Agency for Healthcare Research and Quality; December 2010.

Foy R, Ovretveit J, Shekelle PG, Pronovost PJ, Taylor SL, Dy S, Hempel S, McDonald KM, Rubenstein LV, Wachter RM. The role of theory in research to develop and evaluate the implementation of patient safety practices. BMJ Qual Saf. 2011 May;20(5):453-9.

Shekelle PG, Pronovost PJ, Wachter RM, Taylor SL, Dy SM, Foy R, Hempel S, McDonald KM, Ovretveit J, Rubenstein LV, Adams AS, Angood PB, Bates DW, Bickman L, Carayon P, Donaldson L, Duan N, Farley DO, Greenhalgh T, Haughom J, Lake ET, Lilford R, Lohr KN, Meyer GS, Miller MR, Neuhauser DV, Ryan G, Saint S, Shojania KG, Shortell SM, Stevens DP, Walshe K. Advancing the science of patient safety. Ann Intern Med. 2011 May 17;154(10):693-6.

Ovretveit JC, Shekelle PG, Dy SM, McDonald KM, Hempel S, Pronovost P, Rubenstein L, Taylor SL, Foy R, Wachter RM. How does context affect interventions to improve patient safety? An assessment of evidence from studies of five patient safety practices and proposals for research. BMJ Qual Saf. 2011 Jul;20(7):604-10.

Taylor SL, Dy S, Foy R, Hempel S, McDonald KM, Ovretveit J, Pronovost PJ, Rubenstein LV, Wachter RM, Shekelle PG. What context features might be important determinants of the effectiveness of patient safety practice interventions? BMJ Qual Saf. 2011 Jul;20(7):611-7.

Dy SM, Taylor SL, Carr LH, Foy R, Pronovost PJ, Ovretveit J, Wachter RM, Rubenstein LV, Hempel S, McDonald KM, Shekelle PG. A framework for classifying patient safety practices: results from an expert consensus process. BMJ Qual Saf. 2011 Jul;20(7):618-24.

AHRQ EPCprogram Management of Acute Otitis Media: Update

Shekelle PG, Takata G, Newberry SJ, Coker, T, Limbos M, Chan LS, Timmer M, Suttorp M, Carter J, Motala A, Valentine D, Johnsen B, Shanman R. Management of Acute Otitis Media: Update. Evidence Report/ Technology Assessment No. 198.(Prepared by the Southern California Evidence-based Practice Center under Contract No. 290 2007 10056 I). Rockville, MD: Agency for Healthcare Research and Quality. November 2010.

Coker TR, Chan LS, Newberry SJ, Limbos MA, Suttorp MJ, Shekelle PG, Takata GS. Diagnosis, microbial epidemiology, and antibiotic treatment of acute otitis media in children: a systematic review. JAMA. Nov 17 2010;304(19):2161-2169.

National Institute of Allergy and Infectious Diseases (NIAID) Incidence, Prevalence, Diagnosis, Treatment and Management of Food Allergy

Schneider Chafen, Jennifer J., Sydne Newberry, Marc Riedl, Dena M. Bravata, Margaret Maglione, Marika Suttorp, Vandana Sundaram, Neil M. Paige, Ali Towfigh, Benjamin J. Hulley and Paul G. Shekelle. Prevalence, Natural History, Diagnosis and Treatment of Food Allergy: The State of the Research. Santa Monica, CA: RAND Corporation, August 2010.

Schneider-Chafen, J., S, Newbery, M. Riedl, D. Bravata, M. Maglione, M. Suttorp, V. Sundaram, N. Paige, A. Towfigh, B. Hulley, P.G Shekelle (2010). Diagnosing and Managing Common Food Allergies: A Systematic Review. JAMA. 303(18):1848-56

Health Services Resource Administration (HRSA) Psychosocial Treatment of Autism in Children

Maglione, M., Gans, D., Timbie, J., Das, L., Munjas, B. A., Suttorp, M., & Timmer M. (April 2010). Draft: Systematic Review of the Evidence on Psychosocial and Related Interventions for Children with Autism. Rockville, MD: U.S. Department of Health and Human Services, Health Resources and Services Administration.

Maglione MA, Gans D, Das L, Timbie J, Kasari C. interventions for children with ASD: recommended guidelines and further research needs. Pediatrics. 2012 Nov;130 Suppl 2:S169-78.

RAND, Health Foundation, University of Newcastle Collaboration between primary care and specialists Foy R, Hempel S, Rubenstein L, Suttorp M, Seelig M, Shanman R, Shekelle P: Meta analysis: Effect of Interactive Communication Between Collaborating Primary Care Physicians and Specialists. Ann Intern Med 2010, 152:247-258.